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TranscriptomicsExpression data from Che-1 (AATF) depleted HCT 116 cell line
Che-1 is a RNA Polymerase II binding protein involved in the regulation of gene transcription. Che-1 emerges as an important adaptor that connects transcriptional regulation, cell-cycle progression, checkpoint control, and apoptosis. We have observed that Che-1 depletion sensitizes cells to chemothe...
ORGANISM(S): Homo sapiens 
2013-03-12 | E-GEOD-45009 | biostudies-arrayexpress
GenomicsChe-1/miR-590-3p/TAZ axis sustains multiple myeloma disease
Che-1/miR-590-3p/TAZ axis sustains multiple myeloma disease
PRJNA982174 | ENA
GenomicsChe-1/AATF-induced transcriptionally active chromatin promotes cell proliferation in Multiple Myeloma
Che-1/AATF-induced transcriptionally active chromatin promotes cell proliferation in Multiple Myeloma
PRJNA627186 | ENA
ProteomicsAATF interactome in human Kms27 cells
Multiple myeloma is a hematological neoplasm of plasma cells characterized by an abnormal production of immunoglobulins. Che-1/AATF (Che-1) is an RNA binding protein involved in transcription regulation and highly expressed in this malignancy. In order to better characterize its functions in this ty...
ORGANISM(S): Homo sapiens (Human) 
2022-08-03 | PXD026659 | Pride
Multiple myeloma Aatf 
TranscriptomicsExpression data from Che-1 (AATF) depleted HCT 116 cell line
Che-1 is a RNA Polymerase II binding protein involved in the regulation of gene transcription. Che-1 emerges as an important adaptor that connects transcriptional regulation, cell-cycle progression, checkpoint control, and apoptosis. We have observed that Che-1 depletion sensitizes cells to chemothe...
ORGANISM(S): Homo sapiens 
2013-03-12 | GSE45009 | GEO
UnknownNew species of Eupolyphaga Chopard, 1929 and Pseudoeupolyphaga Qiu & Che, 2024 (Blattodea, Corydioidea, Corydiinae), with notes on their female genitalia.
Not available
S-EPMC11391126 | biostudies-literature
TranscriptomicsExpression data from Che-1 (AATF) depleted SKBR3 and MDA-468 cell lines
Che-1 is a RNA Polymerase II binding protein involved in the regulation of gene transcription. We have observed that Che-1 depletion induces apoptosis in several cancer cells expressing mutated forms of p53. We used microarrays to investigate classes of genes regulated by Che-1 in one of these cell ...
ORGANISM(S): Homo sapiens 
2010-03-05 | GSE20622 | GEO
UnknownValidation of the Investigator Global Assessment of Chronic Hand Eczema (IGA-CHE): a new clinician reported outcome measure of CHE severity.
Not available
S-EPMC10955004 | biostudies-literature
TranscriptomicsChe-1/miR-590-3p/TAZ axis sustains multiple myeloma disease
Multiple myeloma (MM) is a blood disease characterized by the malignant accumulation of monoclonal plasma cells in the bone marrow. Among the pathological consequences of the MM, defects in osteogenesis characterized by osteolytic lesions, osteopenia, and pathologic fractures are frequently describe...
ORGANISM(S): Homo sapiens 
2024-04-10 | GSE234642 | GEO
TranscriptomicsChe-1 sustains hypoxic response of colorectal cancer cells by affecting Hif-1α stabilization
Solid tumors are less oxygenated than normal tissues, and for this reason the cancer cells have developed several molecular mechanisms of adaptation to hypoxic environment. Moreover, his poor oxygenation is a major indicator of an adverse prognosis and leads resistance to standard anticancer treatme...
ORGANISM(S): Homo sapiens 
2017-06-12 | GSE90599 | GEO
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