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TranscriptomicsArray CGH analysis for 29 pancreatic ductal adenocarcinoma (PDAC) samples
Background/Aims: Microarray-based comparative genomic hybridisation (CGH) has allowed high-resolution analysis of DNA copy number alterations across the entire cancer genome. Recent advances in bioinformatics tools enable us to perform a robust and highly sensitive analysis of array CGH data and fac...
ORGANISM(S): Homo sapiens 
2008-12-16 | E-GEOD-9672 | biostudies-arrayexpress
TranscriptomicsS100P is a metastasis-associated gene that facilitates transendothelial migration of pancreatic cancer cells [HG-U133_Plus_2]
We and others have shown that S100P is highly upregulated during the progression of pancreatic cancer. We used microarrays to look at the target genes regulated by S100P in the pancreatic cancer cell line Panc1. Keywords: Gene overexpression We generated stable cell lines by introducing control vec...
ORGANISM(S): Homo sapiens 
2013-08-15 | E-GEOD-19278 | biostudies-arrayexpress
TranscriptomicsS100P is a metastasis-associated gene that facilitates transendothelial migration of pancreatic cancer cells [HG-U133A]
Pancreatic cancer is a devastating disease with both local invasion and distant metastasis. Identifying the genes expressed in liver metastases and signatures of metastatic progression would therefore be of particular importance as they could aid in both recurrence prediction as well as representing...
ORGANISM(S): Homo sapiens 
2013-08-15 | E-GEOD-19279 | biostudies-arrayexpress
TranscriptomicsS100P is a metastasis-associated gene that facilitates transendothelial migration of pancreatic cancer cells [HG-U133B]
Pancreatic cancer is a devastating disease with both local invasion and distant metastasis. Identifying the genes expressed in liver metastases and signatures of metastatic progression would therefore be of particular importance as they could aid in both recurrence prediction as well as representing...
ORGANISM(S): Homo sapiens 
2013-08-15 | E-GEOD-19280 | biostudies-arrayexpress
TranscriptomicsTranscriptional profiling of pancreatic cancer cell lines not expressing or over-expressing S100BP
This SuperSeries is composed of the SubSeries listed below. Refer to individual Series
ORGANISM(S): Homo sapiens 
2014-01-01 | E-GEOD-35199 | biostudies-arrayexpress
TranscriptomicsS100P is a metastasis-associated gene that facilitates transendothelial migration of pancreatic cancer cells
This SuperSeries is composed of the SubSeries listed below. Refer to individual Series
ORGANISM(S): Homo sapiens 
2013-08-15 | E-GEOD-19281 | biostudies-arrayexpress
TranscriptomicsPaclitaxel resistance in ovarian cancer increases oncolytic adenovirus efficacy via upregulated CAR expression and dysfunctional cell cycle control
The microtubule-stabilising drug paclitaxel has activity in relapsed ovarian cancer. However, resistance frequently develops. Oncolytic adenoviruses are a novel cancer therapy, and replicate selectively within and lyse malignant cells, leading to productive infection of neighbouring cells. We fou...
ORGANISM(S): Homo sapiens 
2015-12-10 | E-GEOD-54772 | biostudies-arrayexpress
TranscriptomicsMolecular analysis of precursor lesions in familial pancreatic cancer
Background: With less than a 5% survival rate pancreatic adenocarcinoma (PDAC) is almost uniformly lethal. In order to make a significant impact on survival of patients with this malignancy, it is necessary to diagnose the disease early, when curative surgery is still possible. Detailed knowledge of...
ORGANISM(S): Homo sapiens 
2013-03-27 | E-GEOD-43288 | biostudies-arrayexpress
TranscriptomicsmiRNA profiling of rhabdomyosarcoma-derived exosomes compared to donor cells, using the Affymetrix GeneChip miRNA 3.0 array
Exosomes were isolated by differential centrifugation from the fusion negative human embryonal rhabdomyosarcoma (ERMS) cell lines (JR1, Rh36, and RD) and fusion positive alveolar RMS (ARMS) cell lines (Rh30 and Rh41) and characterized by western blot for exosomal markers. miRNA content of the RMS-de...
ORGANISM(S): Homo sapiens 
2016-12-01 | E-MTAB-5321 | biostudies-arrayexpress
TranscriptomicsExpression data from Tamoxifen resistant Breast Cancer Cell lines
Tamoxifen Resistant (TR) gene profile from Breast cancer cell lines T47D and ZR75-1 with their oestrogen-deprieved conterparts were analysed for gene associated with TR. We used Microarray Affymetrix HU133plus 2.0 chips for gene expression of TR cell lines, normalised them against GEO data available...
ORGANISM(S): Homo sapiens 
2010-12-31 | E-GEOD-22664 | biostudies-arrayexpress
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