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MetabolomicsOptimizing Deconvolution of Chimeric Fragmentation Spectra to reveal molecular structures of complex biological mixtures

Direct infusion mass spectrometry (DI-MS) offers a rapid, high-throughput analysis and, compared to liquid chromatography MS (LC-MS), a different analytical window into the composition of complex biological samples. However, the lack of chromatographic separation in DI-MS results in highly comple...

MTBLS13066 | MetaboLights
TranscriptomicsAssessment of chemical mixtures and ground water effects on Daphnia magna transcriptomics
Small organisms can be used as biomonitoring tools to assess chemicals in the environment. Chemical stressors are especially hard to assess and monitor when present as complex mixtures. Here, Daphnia magna were exposed for 24 hours to five different munitions constituents 2,4,6-trinitrotoluene (TNT)...
ORGANISM(S): Daphnia magna 
2011-06-22 | E-GEOD-30163 | biostudies-arrayexpress
MetabolomicsPlot diversity differentially affects the chemical composition of leaves, roots and root exudates in four subtropical tree species

Plants produce thousands of compounds, collectively called the metabolome, which mediate interactions with other organisms. The metabolome of an individual plant may change according to the number and nature of these interactions. We tested the hypothesis that tree diversity level affects the met...

2021-08-09 | MTBLS1968 | MetaboLights
TranscriptomicsTranscriptional impact of organophosphate and metal mixtures on olfaction: copper dominates the chlorpyrifos-induced response in adult zebrafish.
Chemical exposures in fish have been linked to loss of olfaction leading to an inability to detect predators and prey and decreased survival. However, the mechanisms underlying olfactory neurotoxicity are not well characterized, especially in environmental exposures which involve chemical mixtures. ...
ORGANISM(S): Danio rerio 
2013-05-21 | E-GEOD-47039 | biostudies-arrayexpress
TranscriptomicsAssessment of chemical mixtures and ground water effects on Daphnia magna transcriptomics
Small organisms can be used as biomonitoring tools to assess chemicals in the environment. Chemical stressors are especially hard to assess and monitor when present as complex mixtures. Here, Daphnia magna were exposed for 24 hours to five different munitions constituents 2,4,6-trinitrotoluene (TNT)...
ORGANISM(S): Daphnia magna 
2011-06-23 | GSE30163 | GEO
GenomicsEnvironmental chemical mixtures reprogram mammary epithelial development to epigenetic states associated with breast cancer
Environmental chemical mixtures reprogram mammary epithelial development to epigenetic states associated with breast cancer
PRJNA1451208 | ENA
TranscriptomicsGene expression profiling of mussels treated with two chemical mixtures
We examined gene expression profiling of mussels treated with two chemical mixtures composed by heavy metals or organic compounds, both including genotoxic agents (cadmium, benzo[a]pyrene, 1-nitro/amino-pyrene) and other contaminants (cupper, mercury, fluoranthene, TCDD). For digestive gland one RNA...
ORGANISM(S): Mytilus galloprovincialis 
2006-10-10 | GSE2183 | GEO
UnknownInvestigation on Combined Inhalation Exposure Scenarios to Biocidal Mixtures: Biocidal and Household Chemical Products in South Korea.
Not available
S-EPMC7913984 | biostudies-literature
GenomicsEnvironmental chemical mixtures reprogram mammary epithelial development to epigenetic states associated with breast cancer [Bisulfite-Seq]
Environmental chemical mixtures reprogram mammary epithelial development to epigenetic states associated with breast cancer [Bisulfite-Seq]
PRJNA1459227 | ENA
TranscriptomicsTranscription profiling of rat liver and kidney (F344 strain) following exposure to benzene, trichloroethylene, methyl mercury and their mixtures
The present research aimed to study the interaction of three chemicals, methyl mercury, benzene and trichloroethylene, on mRNA expression alterations in rat liver and kidney measured by microarray analysis. These compounds were selected on presumed different modes of action. The chemicals were admi...
ORGANISM(S): Rattus norvegicus 
2007-09-15 | E-TOXM-30 | biostudies-arrayexpress
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