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TranscriptomicsPlatelet-secreted microRNA-223 promotes endothelial cell apoptosis induced by advanced glycation end products via targeting the insulin-like growth factor 1 receptor
Platelets contain abundant miRNAs, however, the biogenesis pathway of miRNAs in anucleate platelets is unclear. Platelet-rich plasma was diluted in washing buffer and the platelet suspension was centrifuged to isolated pure platelets.Finally, platelets were recovered in suspension buffer at the conc...
ORGANISM(S): Homo sapiens 
2014-02-04 | E-GEOD-51453 | biostudies-arrayexpress
UnknownA Transcriptome-Level Study Identifies Changing Expression Profiles for Ossification of the Ligamentum Flavum of the Spine.
Not available
S-EPMC6120750 | biostudies-literature
TranscriptomicsPreactivation of the interferon signaling in liver is correlated with non-response to interferon alpha therapy in patients chronically infected with hepatitis B virus
To screen the differentially expressed genes between responders(Rs) and nonresponders(NRs) in CHB patients treated with IFN-α, and to explore the molecular basis for treatment failure.Expression profiling was performed on percutaneous needle liver biopsy specimens taken before therapy.Gene expressio...
ORGANISM(S): Homo sapiens 
2011-03-01 | E-GEOD-27555 | biostudies-arrayexpress
ProteomicsHuman hepatocellular carcinoma MHCC97H proteome
In this work, we generated a MHCC97H proteome datasets by In-gel digestion on Orbitrap Fusion Lumos. We systematically compared RNC-seq and Ribo-seq in the context of proteome identification, especially when identifying protein isoforms from AS. We also demonstrated that the single-molecule long rea...
ORGANISM(S): Homo sapiens (Human) 
2022-06-28 | PXD032201 | Pride
Human In-gel digestion Liver Mhcc97h Lc-ms/ms 
ProteomicsProteomes of Spirodela polyhriza under different trophic modes
The greater duckweed (Spirodela polyrhiza 7498) exhibits trophic diversity (photoautotrophic, heterotrophic, photoheterotrophic, and mixotrophic growth) depending on the availability of exogenous organic carbon sources and light. Here, we show that the ability to transition between various trophic g...
ORGANISM(S): Spirodela Polyrhiza 
2023-02-27 | PXD040410 |
UnknownThe liver-enriched lnc-LFAR1 promotes liver fibrosis by activating TGFβ and Notch pathways.
Not available
S-EPMC5529527 | biostudies-literature
UnknownEffectiveness of various COVID-19 vaccine regimens among 10.4 million patients from the National COVID Cohort Collaborative during Pre-Delta to Omicron periods - United States, 11 December 2020 to 30 June 2022.
Not available
S-EPMC10730423 | biostudies-literature
UnknownLncRNA Airn maintains LSEC differentiation to alleviate liver fibrosis via the KLF2-eNOS-sGC pathway.
Not available
S-EPMC9520944 | biostudies-literature
MetabolomicsMulti-omics analysis reveals ToMMV-induced regulation of amino acid and phenylpropanoid biosynthesis pathways affecting tomato fruit quality and resistance

Tomato mottle mosaic virus (ToMMV) is a major threat to cultivating tomatoes and other solanaceous plants. Here, an infectious clone of the ToMMV Huludao isolate was constructed, and ToMMV infection significantly reduces soluble sugar, soluble phenolic and vitamin C ...

2025-09-01 | MTBLS12864 | MetaboLights
ProteomicsProteogenomic Landscape of Breast Ductal Carcinoma Reveals Tumor Progression Characteristics and Therapeutic Targets
In this study, we performed integrated multi-omics analyses using genomic (n = 79), transcriptomic (n = 42), proteomic (n = 224), and phosphoproteomic (n = 49) data collected from 224 samples from 168 patients with malignant and benign breast diseases. Our data revealed the characteristics of the li...
ORGANISM(S): Homo Sapiens 
PXD040750 |
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