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Intracranial aneurysms (IAs) are benign cerebrovascular maladies characterized by pathological dilatation in the walls of intracranial arteries. However, spontaneous subarachnoid hemorrhage (SAH) resulting from aneurysm rupture poses a grave threat to the patient's life. Accumulating evidence imp...

2024-12-13 | MTBLS10263 | MetaboLights
Temporal lobe epilepsy (TLE) is the most frequent type of focal epilepsy in adults, typically resistant to pharmacological treatment and mostly present with cognitive impairment and psychiatric comorbidities. The most common neuropathological hallmark in TLE patients is hippocampal sclerosis(HS). Ho...
ORGANISM(S): Homo sapiens (Human) 
2021-01-18 | PXD023048 | Pride
Data from ProteomeXchange, PXD ID: PXD000773. File: zhanghongyu_20110913_13.mzml. Published as part of . From the Abstract: {{i}} Activated hepatic stellate cell (HSC) is the main myofibroblast cell in the liver fibrosis (LF). An important characteristic of the recovery of LF is not only the apopto...
ORGANISM(S): Homo_sapiens_viruses, Human 
Activated hepatic stellate cell (HSC) is the main myofibroblast cell in the liver fibrosis(LF). An important characteristic of the recovery of LF is not only the apoptosis of activated HSCs but also reversal of myofibroblast-like phenotype to a quiescent-like phenotype. Understanding the changes of ...
ORGANISM(S): Homo sapiens (Human) 
2014-08-11 | PXD000773 | Pride
Interferon (IFN)-γ-producing CD8+ T cells are involved in control of Mycobacterium tuberculosis (Mtb) infection, in part by promoting antimicrobial activities of macrophages. Whether Mtb counters these responses, particularly during the hypoxic conditions that arise within granulomas during infectio...
ORGANISM(S): Mycobacterium tuberculosis OFXR-32 
2024-08-10 | PXD050258 | Pride
Triploid oysters have poor gonadal development, which can not only bring higher economic benefits but also have a potential application in the genetic containment for aquaculture. However, the key factors that influence germ cell development in triploid oysters remain unclear. In this study, data-i...
ORGANISM(S): Crassostrea Gigas 
2021-08-22 | PXD028056 |
Lysine-succinylation is a subtype of protein acylation associated with metabolic regulation of succinyl-CoA in the TCA cycle. Deficiency of succinyl-CoA synthetase (SCS), the TCA-cycle enzyme catalyzing the reversible conversion of succinyl-CoA to succinate, leads to mitochondrial encephalomyopathy ...
ORGANISM(S): Mus Musculus (ncbitaxon:10090) 
2022-06-21 | MSV000089697 | MassIVE
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