Sort   by:  
 Page size 
MetabolomicsBased on the Metabolomic Approach the Energy Metabolism Responses of Oriental River Prawn Macrobrachium nipponense Hepatopancreas to Acute Hypoxia and Reoxygenation
Hypoxia represents a major physiological challenge for prawns and is a problem in aquaculture. Therefore, an understanding of the metabolic response mechanism of economically important prawn species to hypoxia and re-oxygenation is essential. However, little is known about the intrinsic mechanisms b...
2021-05-17 | MTBLS584 | MetaboLights
ProteomicsNRBF2 orchestrates autophagic flux and adult hippocampal neurogenesis in chronic stress-induced depression
By precisely dissected LC-MS/MS for proteomics and phosphoproteomics, we found that deletion of NRBF2 disrupts neurogenesis-related protein network in the DG, such as neurogenesis, cell development, cell morphogenesis, cellular homeostasis, and synaptic plasticity.
ORGANISM(S): Mus musculus (Mouse) 
2023-10-24 | PXD034382 | Pride
Autophagy Mouse Nrbf2 Dentate gyrus 
ProteomicsProteins that bind to IGFBP7 in cadmium-induced hepatorenal fibrosis
Through liquid chromatography-mass spectrometry (LC-MS/MS) analysis, we analyzed the differential proteins in cadmium-induced mouse kidney and liver tissues, and looked for the potential targets of IGFBP7
ORGANISM(S): Mus Musculus 
PXD057126 |
UnknownA comprehensive assessment of RNA-seq accuracy, reproducibility and information content by the Sequencing Quality Control Consortium.
We present primary results from the Sequencing Quality Control (SEQC) project, coordinated by the US Food and Drug Administration. Examining Illumina HiSeq, Life Technologies SOLiD and Roche 454 platforms at multiple laboratory sites using reference RNA samples with built-in controls, we assess RNA ...
S-EPMC4321899 | biostudies-literature
UnknownA global reference for human genetic variation.
The 1000 Genomes Project set out to provide a comprehensive description of common human genetic variation by applying whole-genome sequencing to a diverse set of individuals from multiple populations. Here we report completion of the project, having reconstructed the genomes of 2,504 individuals fro...
S-EPMC4750478 | biostudies-literature
UnknownGWAS and colocalization analyses implicate carotid intima-media thickness and carotid plaque loci in cardiovascular outcomes.
Carotid artery intima media thickness (cIMT) and carotid plaque are measures of subclinical atherosclerosis associated with ischemic stroke and coronary heart disease (CHD). Here, we undertake meta-analyses of genome-wide association studies (GWAS) in 71,128 individuals for cIMT, and 48,434 individu...
S-EPMC6277418 | biostudies-literature
UnknownStroke genetics informs drug discovery and risk prediction across ancestries.
Previous genome-wide association studies (GWASs) of stroke - the second leading cause of death worldwide - were conducted predominantly in populations of European ancestry1,2. Here, in cross-ancestry GWAS meta-analyses of 110,182 patients who have had a stroke (five ancestries, 33% non-Eu...
S-EPMC9524349 | biostudies-literature
UnknownDe novo mutations across 1,465 diverse genomes reveal mutational insights and reductions in the Amish founder population.
De novo mutations (DNMs), or mutations that appear in an individual despite not being seen in their parents, are an important source of genetic variation whose impact is relevant to studies of human evolution, genetics, and disease. Utilizing high-coverage whole-genome sequencing data as part of the...
S-EPMC7007577 | biostudies-literature
UnknownPrevalence, associated factors and outcomes of pressure injuries in adult intensive care unit patients: the DecubICUs study.

Purpose

Intensive care unit (ICU) patients are particularly susceptible to developing pressure injuries. Epidemiologic data is however unavailable. We aimed to provide an international picture of the extent of pressure injuries and factors associated with ICU-acquired pressure injuries in ad...
S-EPMC7880913 | biostudies-literature
Sort   by:  
 Page size