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MetabolomicsAnti-anemia drug FG4592 retards the AKI to CKD transition by improving vascular regeneration and anti-oxidative capability (day 21)

Acute kidney injury (AKI) is a known risk factor for the development of chronic kidney disease (CKD), with no satisfactory strategy to prevent the progression of AKI to CKD. Damage to the renal vascular system and subsequent hypoxia are common contributors to both AKI and CKD. Hypoxia inducible f...

2021-07-22 | MTBLS3003 | MetaboLights
MetabolomicsAnti-anemia drug FG4592 retards the AKI to CKD transition by improving vascular regeneration and anti-oxidative capability (day 10)

Acute kidney injury (AKI) is a known risk factor for the development of chronic kidney disease (CKD), with no satisfactory strategy to prevent the progression of AKI to CKD. Damage to the renal vascular system and subsequent hypoxia are common contributors to both AKI and CKD. Hypoxia inducible f...

2021-07-22 | MTBLS3056 | MetaboLights
ProteomicsLactylome analysis reveals potential target modified proteins in the retina of form-deprivation myopia
Myopia has become the major cause of visual impairment worldwide. Although the pathogenesis of myopia remains controversial, proteomics studies suggest that dysregulation of retinal metabolism is potentially involved in the pathology of myopia. Lysine lactylation of proteins plays a key role in regu...
ORGANISM(S): Cavia porcellus (Guinea pig) 
2024-10-17 | PXD046495 | Pride
Lysine lactylation Form-deprivation myopia Lactate Aerobic glycolysis Retina 
ProteomicsIntegrative analysis of microRNAome, transcriptome, and proteome during the limb regeneration of Cynops orientalis
Salamanders completely regenerate their limbs after amputation. Thus, these animals are unique models to investigate the mechanisms modulating the regeneration in vertebrates. To investigate the influence of microRNAs on the newt limb regeneration, an integrative analysis of microRNAome, transcript...
ORGANISM(S): Cynops Orientalis 
2018-12-17 | PXD012091 |
ProteomicsSerum proteomics data of sepsis
This study analysed the proteome of serum from patients with sepsis to characterize the pathological mechanism and pathways involved in sepsis.
ORGANISM(S): Homo Sapiens 
2021-07-22 | PXD027485 |
ProteomicsInsight of novel biomarkers for papillary thyroid carcinoma through multi-omics
Our multi-omics analysis of local patients demonstrated significant distinctions compared to TCGA-THCA cohorts, highlighting the unique genetic characteristics of Chinese individuals with PTC. We identified novel biomarkers that hold potential for diagnosis and prognosis of PTC. Furthermore, develop...
ORGANISM(S): Homo Sapiens 
PXD044815 |
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