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It has been shown that in mammalian cells alternative transcription initiation is extensively regulated during development and across cell-types, which confers dynamic transcript 5’UTR repertoire. However it is underexplored how the heterogeneity of 5’UTR isoforms would affect the downstream ste...
ORGANISM(S): Mus musculus 
Because of limited clinical cases, the natural history of occult breast cancer (OBC) is poorly understood and its proteomic signature remains unknown. We performed a quantitative proteomic analysis for tissue samples of metastatic lymph nodes from 3 OBC patients, and paired tissue samples of metasta...
ORGANISM(S): Homo sapiens (Human) 
2025-01-31 | PXD052744 | Pride
These microarrays are part of a study where a comparison was made between the change in transcription and H3K4 mono-, di-, and tri-methylation levels (via ChIP-seq) in the Arabidopsis thaliana genome when plants are subjected to water deficit stress. Water deficit stress causes a large number of gen...
ORGANISM(S): Arabidopsis thaliana 
We collected over 8000 mouse embryos of each developmental stage (zygote, 2-cell, 4-cell, 8-cell, morula, blastocyst) and performed tandem mass tag (TMT)-based quantitative mass spectrometry and identified nearly 5000 proteins for each stage. In-depth analysis indicates that protein expression profi...
ORGANISM(S): Mus Musculus (ncbitaxon:10090) 
2015-12-10 | MSV000079417 | MassIVE
Characterizing the tumor microenvironment at the molecular level is essential for understanding the mechanisms of tumorigenesis and evolution. However, the specificity of the blood proteome in localized region of the tumor and its linkages with other systems is difficult to investigate. Here, we pro...
ORGANISM(S): Homo Sapiens 
2023-07-20 | PXD043970 |
Cancer cells undergo transcriptional reprogramming to drive tumor progression and metastasis. Here, we identified the transcriptional complex, NELF (Negative elongation factor), as an important regulator of this process. Using cancer cell lines and patient-derived tumor organoids, we demonstrated th...
ORGANISM(S): Homo Sapiens (human) 
We developed a pulse-chase method in where fully SILAC (heavy, medium-heavy and Light) labelled cells were pulsed with Azidohomoalanine (AHA) and then chased for different length of times. In addition, steady state protein levels comparing the RPE- and RPE-1 trisomic cells by standard SILAC labeling...
ORGANISM(S): Homo Sapiens (ncbitaxon:9606) 
2017-03-31 | MSV000080831 | MassIVE
Searching for baseline proteins that contribute to the individual response to RS intervention
ORGANISM(S): Homo Sapiens 
2025-09-24 | PXD068798 |
Phosphorylation sites identified at the C-terminus of mGlu5 by mass spectrometry analysis
ORGANISM(S): Homo Sapiens 
2026-04-01 | PXD076479 |
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