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TranscriptomicsGene expression in human umbilical cord vein and artery endothelial cells under physiological chronic normoxia (3% O2, PCN) and standard culture normoxia (21% O2, SCN)
Endothelial cells, and many other types of cells too, physiologically reside in low O2 environments (~ 2-13% O2 or 15-60 mmHg pO2; [PCN]) relevantly to atmospheric O2 (~ 21% or 160 mmHg pO2 at sea level) in vivo. Such PCN is critical for endothelial functions. The majority of our current knowledge ...
ORGANISM(S): Homo sapiens 
2013-08-30 | E-GEOD-49958 | biostudies-arrayexpress
TranscriptomicsKRAS-induced transcription analysis in immortalized pancreatic cells
We utilized non-transformed, human pancreatic ductal epithelial (HPDE) cells, previously engineered with the E6 and E7 proteins of the HPV16 virus to emulate loss of p53 and inactivation of the Rb pathway, respectively. Given the frequent activation of KRAS (>90% PDAC tumors) and its early role in p...
ORGANISM(S): Homo sapiens 
2016-01-19 | E-GEOD-58055 | biostudies-arrayexpress
UnknownPolarization-Sensitive Optical Coherence Tomography Imaging of Posterior Staphyloma Edges in Eyes With High Myopia.
Not available
S-EPMC12338364 | biostudies-literature
UnknownWhorl-Like Collagen Fiber Arrangement Around Emissary Canals in the Posterior Sclera.
Not available
S-EPMC11927319 | biostudies-literature
UnknownPossible Extension of Inner Scleral Fibers Into the Peripapillary Sclera Detected by Polarization-Sensitive OCT.
Not available
S-EPMC12798758 | biostudies-literature
UnknownA rare dominant allele <i>DYSOC1</i> determines seed coat color and improves seed oil content in <i>Brassica napus</i>.
Not available
S-EPMC11698099 | biostudies-literature
MetabolomicsSpatiotemporal determination of metabolite activities in the corneal epithelium on a chip
The corneal epithelial barrier maintains the metabolic activities of the ocular surface by regulating membrane transporters and metabolic enzymes responsible for the homeostasis of the eye as well as the pharmacokinetic behavior of drugs. Despite its importance, no established biomimetic in vitro me...
2021-07-13 | MTBLS2274 | MetaboLights
UnknownAn ISG15-Based High-Throughput Screening Assay for Identification and Characterization of SARS-CoV-2 Inhibitors Targeting Papain-like Protease.
Not available
S-EPMC11359932 | biostudies-literature
UnknownBroad-Spectrum Small-Molecule Inhibitors Targeting the SAM-Binding Site of Flavivirus NS5 Methyltransferase.
Not available
S-EPMC10436986 | biostudies-literature
UnknownInhibition of PIP4Kγ ameliorates the pathological effects of mutant huntingtin protein.
Not available
S-EPMC5743427 | biostudies-literature
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