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TranscriptomicsResponses to P. aeruginosa infection - Shapira
Synchronized C. elegans cultures were prepared using standard techniques (http://cmgm.stanford.edu/~kimlab/index_methods.html). Live young adult worms were split between NG plates pre-seeded with the non-pathogenic E. coli strain OP50 or the Pseudomonas aeruginosa clinical isolate PA14 and incubated...
ORGANISM(S): Caenorhabditis elegans 
2010-07-01 | E-GEOD-5584 | biostudies-arrayexpress
TranscriptomicsRNA-seq of M-CSF differentiated human peripheral monocyte-derived macrophages (MDMs) activated with short exposure (3hours) to LPS, or long exposure (24 hours) to LPS, LPS with IFNγ, IFNγ, IL-4, IL-10, and dexamethasone
The goal of this experiment was to validate a classification model built on other bulk transcriptomic data that was capable of identifying in vitro stimulated M-CSF differentiated macrophages. Specifically, the classification model was capable of distinguishing: M-LPSearly (2-4 hours) M-LPSlate (18...
ORGANISM(S): Homo sapiens 
2020-01-06 | E-MTAB-7572 | biostudies-arrayexpress
TranscriptomicsHigh salt primes a specific activation state of macrophages, M(Na)
Purpose: Investigate effects of high salt on human macrophage activation Methods: Human monocytes-derived macrophages were treated by additional 51mM NaCl for 24 hours (NaCl groups) or not (Control groups). mRNA profiles were generated by RNA-Seq, in triplicate, using Ion proton（Life tech). qRT–PCR ...
ORGANISM(S): Homo sapiens 
2015-09-23 | E-GEOD-68482 | biostudies-arrayexpress
TranscriptomicsTranscription profiling of human RKO cells after induction of KLF4 for different lengths of time
A stably transfected inducible system for KLF4 was established in RKO cells as previously described (Chen et al., 2001; Chen et al., 2003). This cell line, called EcR-RKO/KLF4, contains stably transfected receptors for the insect hormone, ecdysone (EcR), and a full-length mouse KLF4 cDNA driven by ...
ORGANISM(S): Homo sapiens 
2007-06-21 | E-GEOD-3113 | biostudies-arrayexpress
UnknownRole of malectin in Glc(2)Man(9)GlcNAc(2)-dependent quality control of α1-antitrypsin.
Not available
S-EPMC3183012 | biostudies-literature
TranscriptomicsTranscription profiling of human liver cancer samples
Experiments used in Figure one of the HCC paper by Chen X, et al.
ORGANISM(S): Homo sapiens 
2008-03-12 | E-SMDB-1164 | biostudies-arrayexpress
TranscriptomicsTranscriptional profiling of ATCC46645 strain and isogenic M-NM-^TpacC Aspergillus fumigatus mutant during murine infection
In lung diseases caused by the major mould pathogen Aspergillus fumigatus the pulmonary epithelium is destroyed by invasive growth of fungal hyphae, a process thought to require fungal proteases. Here we show that the A. fumigatus pH-responsive transcription factor PacC governs expression of secrete...
ORGANISM(S): Aspergillus fumigatus 
2014-10-20 | E-GEOD-54810 | biostudies-arrayexpress
TranscriptomicsMapping DNA structural variation in dogs
DNA structural variation (SV) comprises a major portion of genetic diversity, but its biological impact is unclear. We propose that the genetic history and extraordinary phenotypic variation of dogs make them an ideal mammal in which to study the effects of SV on biology and disease. The hundreds of...
ORGANISM(S): Canis lupus familiaris 
2010-05-22 | E-GEOD-18317 | biostudies-arrayexpress
UnknownPNPLA3 I148M variant in nonalcoholic fatty liver disease: demographic and ethnic characteristics and the role of the variant in nonalcoholic fatty liver fibrosis.
Not available
S-EPMC4299331 | biostudies-literature
TranscriptomicsGastric Cancer Study GC_126
126 gastric tissues (90 tumor, 14 lymphnode and 22 normal) assayed using 44K human arrays against common reference (CRG). Published by Leung et al, PNAS, 2002 (PubMed ID 12456890) and Chen et al, MBC, 2003. A clinical history design type is where the organisms clinical history of diagnosis, treatmen...
ORGANISM(S): Homo sapiens 
2010-06-10 | E-GEOD-2701 | biostudies-arrayexpress
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