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MetabolomicsPu-erh tea and theabrownin ameliorate metabolic syndrome in mice via potential microbiota-gut-liver-brain interactions
Metabolic syndrome (MS) is a common metabolic disorder characterized by obesity, insulin resistance, cardiovascular disease and gut microbiota dysbiosis. Pu-erh tea and its ingredient theabrownin have known functions on the reduction of body weight gain and fat accumulation. However, few studies sys...
2024-09-25 | MTBLS2594 | MetaboLights
MetabolomicsTheabrownin from Pu-erh tea attenuates hypercholesterolemia via modulation of gut microbiota and bile acid metabolism
Pu-erh tea displays cholesterol-lowering properties, but the underlying mechanism has not been elucidated. Theabrownin is one of the most active and abundant pigments in Pu-erh tea. Here, we show that theabrownin alters the gut microbiota in mice and humans, predominantly suppressing microbes associ...
2021-11-18 | MTBLS1259 | MetaboLights
GenomicsTwo distinct auto-regulatory loops operate at the Pu.1 locus in B cells and myeloid cells
The transcription factor PU.1 occupies a central role in controlling myeloid and early B cell development and its correct lineage-specific expression is critical for the differentiation choice of hematopoietic progenitors. However, little is known of how this tissue-specific pattern is established. ...
ORGANISM(S): Mus musculus 
2011-02-21 | E-GEOD-26550 | biostudies-arrayexpress
UnknownIntegrated Meta-omics Approaches To Understand the Microbiome of Spontaneous Fermentation of Traditional Chinese Pu-erh Tea.
Not available
S-EPMC6867877 | biostudies-literature
UnknownMetabolites profiling reveals the dynamic changes of non-volatiles in Pu-erh during Ganpu tea processing.
Not available
S-EPMC10534103 | biostudies-literature
ProteomicsA systemic view of microbial ecology in spontaneous fermentation of Chinese traditional pu-erh tea
To study the microbial functions, metaproteomes were extracted from 36 samples of fermented tea leaves and subjected to LC-MS/MS analyses. The MS/MS data were searched against the UniProt-protein database of the dominant microorganisms in the sample as identified by previous meta-barcoding analysis....
ORGANISM(S): Aspergillus Thermomyces Rasamsonia 
2019-01-03 | PXD012223 |
UnknownConstrained chromatin accessibility in PU.1-mutated agammaglobulinemia patients.
Not available
S-EPMC8105723 | biostudies-literature
UnknownEffects of Geographical Origin and Tree Age on the Stable Isotopes and Multi-Elements of Pu-erh Tea.
Not available
S-EPMC10855849 | biostudies-literature
UnknownGenetic perturbation of PU.1 binding and chromatin looping at neutrophil enhancers associates with autoimmune disease.
Not available
S-EPMC8052402 | biostudies-literature
UnknownInvestigation into the Adsorption Mechanism of Three Varieties of Carboxylated Graphene Oxide for Pentahydrate Actinide (An = Pa-Pu) Compounds.
Not available
S-EPMC12489631 | biostudies-literature
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