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GenomicsOGT, H2B S112GlcNAc, TET2 ChIP-seq results
TET2 directly interacts with OGT, which is important for the chromatin association of OGT in vivo. Although this specific interaction does not regulate the enzymatic activity of TET2, it facilitates OGT-dependent histone O-GlcNAcylation. Moreover, OGT associates with TET2 at transcription starting s...
ORGANISM(S): Mus musculus 
2012-12-11 | E-GEOD-41720 | biostudies-arrayexpress
ProteomicsCircuit-wide Proteomics Profiling Reveals Brain Region-specific Protein Signatures in the WKY Rats with Endogenous Depression
Major depressive disorder (MDD) is considered as a neural circuit-based polygene syndrome that is mainly triggered by genetic susceptibility and stress factors. The present study employed the Wistar Kyoto (WKY) rat as an animal model with endogenous depression to further investigate the molecular ba...
ORGANISM(S): Rattus norvegicus (Rat) 
2022-10-13 | PXD029079 | Pride
Depression  wistar kyoto rats  proteomics  medial prefrontal cortex  nucleus accumbens  hippocampus 
TranscriptomicsExpression data from ES cells
TET2 directly interacts with OGT, which is important for the chromatin association of OGT in vivo. Although this specific interaction does not regulate the enzymatic activity of TET2, it facilitates OGT-dependent histone O-GlcNAcylation. Moreover, OGT associates with TET2 at transcription starting s...
ORGANISM(S): Mus musculus 
2012-12-11 | E-GEOD-41721 | biostudies-arrayexpress
TranscriptomicsExpression profiling of Drosophila mushroom bodies
We performed mRNA-seq of dissected Drosophila mushroom bodies, comparing to whole brain and testis mRNA seq of MB, brain and testis
ORGANISM(S): Drosophila melanogaster 
2012-02-01 | E-GEOD-33783 | biostudies-arrayexpress
GenomicsH2A.B and MeDIP sequence result
H2A.B is a unique histone H2A variant that shares only 40 ~ 50 % sequence identity with canonical H2A. It has only been identified in mammals and has quickly evolved with remarkable sequence diversity among different species. H2A.B is ubiquitously expressed in most cells and tissues. It is mainly de...
ORGANISM(S): Mus musculus 
2013-12-24 | E-GEOD-48892 | biostudies-arrayexpress
ProteomicsSuccinylation modification provides a new sight in the treatment of immunocompromised populations with drug-resistant Aspergillus fumigatus infection
The invasive infection of Aspergillus fumigatus poses a serious threat to human health worldwide, especially in immunocompromised patients. At present, triazole drugs are the most common antifungal drugs for aspergillosis. However, due to the emergence of drug-resistant strains, the effect of triazo...
ORGANISM(S): Aspergillus Fumigatus 
2023-02-15 | PXD040137 |
TranscriptomicsGenome-wide comparative ChIP-seq data of CTCF and RNA-seq data in Drosophila white prepupa on Illumina Genome Analyzer
This is a dataset which comprises the following two different kinds of genomic data in Drosophila species: First, triplicate ChIP-seq data of CTCF (CCCTC binding factor) binding profiles in each of the four closely related Drosophila species : Drosophila melanogaster, Drosophila simulans, Drosophil...
ORGANISM(S): Drosophila simulans 
2012-11-08 | E-GEOD-24449 | biostudies-arrayexpress
TranscriptomicsExpression data from ES cells
H2A.B is a unique histone H2A variant that shares only 40 ~ 50 % sequence identity with canonical H2A. It has only been identified in mammals and has quickly evolved with remarkable sequence diversity among different species. H2A.B is ubiquitously expressed in most cells and tissues. It is mainly de...
ORGANISM(S): Mus musculus 
2013-12-24 | E-GEOD-48446 | biostudies-arrayexpress
TranscriptomicsExpression profiling of Drosophila testes
We performed mRNA-seq of dissected testes of multiple Drosophila species and RNAi animals mRNA seq of testis
ORGANISM(S): Drosophila yakuba 
2012-05-01 | E-GEOD-36764 | biostudies-arrayexpress
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