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ProteomicsProteomic profiling and molecular reclassification of high-grade serous ovarian cancer
In this study, we performed a comprehensive proteomic analysis of 116 primary tumor tissues from HGSOC patients. Our findings offer valuable insights into HGSOC’s molecular landscape, which could inform future biological studies, drug discovery, and the development of targeted therapies.
ORGANISM(S): Homo Sapiens 
2026-02-12 | PXD074808 |
ProteomicsKDM6A downregulation promotes tumor-prone cytokines expression in cancer-associated fibroblasts by activating enhancers
co-IP assays demonstrate that KDM6A is bound to WDR5, facilitating its association with the COMPASS complex and the polycomb repressive complex at the expected target loci.
ORGANISM(S): Homo Sapiens 
2024-12-04 | PXD058594 |
ProteomicsiTRAQ-based proteomic analysis of the regulation for fengycin production by PhoPR two-component system in Bacillus subtilis strain NCD-2
The PhoPR two-component system regulated fengycin production by regulating the biosynthesis of branched amino acids in Bacillus subtilis strain NCD-2
ORGANISM(S): Halobacterium Salinarum 
2020-12-25 | PXD023319 |
ProteomicsQuantitative proteomics reveals the antibiotics adaptive mechanism of Aeromonas hydrophila in kanamycin stress
Aeromonas hydrophila is a widespread opportunistic pathogen of aquatic fishes in freshwater habitats. The current emergence of antimicrobial-resistant A. hydrophila has been reported in the world while the bacterial antibiotics adaptive mechanism is still largely known. In this study, using quantita...
ORGANISM(S): Aeromonas Hydrophila Subsp. Hydrophila Al09-71 
2022-04-25 | PXD031300 |
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