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UnknownEvaluation of BGJ398, a Fibroblast Growth Factor Receptor 1-3 Kinase Inhibitor, in Patients With Advanced Solid Tumors Harboring Genetic Alterations in Fibroblast Growth Factor Receptors: Results of a Global Phase I, Dose-Escalation and Dose-Expansion Study.
Not available
S-EPMC6865065 | biostudies-literature
TranscriptomicsTranscriptomics and Metabolomics of 10 - 28 day post anthesis cotton fiber from Gossypium hirsutum and Gossypium barbadense
Purpose: The goal of this experiment was to use RNA-seq to compare the two commercial cotton species Gossypium hirsutum and Gossypium barbadense and determine what transcripts may account for the better fiber quality in the latter. Methods: RNA was extracted from Gossypium barbadense or Gossypium hi...
ORGANISM(S): Gossypium barbadense 
2015-06-26 | E-GEOD-64958 | biostudies-arrayexpress
UnknownA non-canonical role of the inner kinetochore in regulating sister-chromatid cohesion at centromeres
Not available
S-SCDT-10_1038-S44318-024-00104-6 | biostudies-other
ProteomicsRegulation of the PKD2 channel function and associated disease phenotypes by RASSF4
Autosomal dominant polycystic kidney disease (ADPKD) is one of the most common monogenic genetic disorders, caused by mutations in receptor PKD1 or ion channel PKD2, and is characterized by progressive renal cyst development with additional hepatic and extrarenal manifestations. As effective treatme...
ORGANISM(S): Homo Sapiens 
2026-02-13 | PXD074819 |
ProteomicsLiver proteomics investigations into hypothyroidism treated with Atractylodis Macrocephalae Rhizome
Hypothyroidism model rats were established with PTU (10 mg•kg-1•d-1) and treated with Atractylodis Macrocephalae Rhizome and its fractions (volatile oil fraction, lactones fraction, atractyloside fraction, oligosaccharide fraction, and crude polysaccharide fraction) for 20 d. The experiment (having ...
ORGANISM(S): Rattus Rattus 
2021-03-04 | PXD024535 |
ProteomicsDual-Proximity Labeling Strategy Identifies TrxR1 as a Cuproprotein that Regulates Apoptosis via Caspase-3 S-Nitrosylation (1)
Copper (Cu) performs essential structural and functional roles in all aerobic organisms, but identifying natural cuproproteins through traditional affinity methods is hindered by the variety of copper ligand combinations and binding locations in proteins. Here, using ATOX1 as a bait, fused with the ...
ORGANISM(S): Homo Sapiens 
PXD068622 |
ProteomicsDual-Proximity Labeling Strategy Identifies TrxR1 as a Cuproprotein that Regulates Apoptosis via Caspase-3 S-Nitrosylation (2)
Copper (Cu) performs essential structural and functional roles in all aerobic organisms, but identifying natural cuproproteins through traditional affinity methods is hindered by the variety of copper ligand combinations and binding locations in proteins. Here, using ATOX1 as a bait, fused with the ...
ORGANISM(S): Homo Sapiens 
PXD068649 |
ProteomicsProteome of uterine cavity fluid in female rattus
The injection with GnIH/saline through the lateral ventricle. At 6 h after injection, the protein components of rats in the experimental and control groups were analyzed using Liquid Chromatography (LC)-Mass Spectrometry (MS)/MS.
ORGANISM(S): Rattus Rattus 
2022-10-31 | PXD037826 |
ProteomicsMechanisms underlying Florfenicol-induced stem cell toxicity using iTRAQ
iTRAQ-based proteomics was performed to explore the mechanism underlying Florfenicol-induced stem cell toxicity and assess the overall protein changes in P19SCs post FLO treatment.
ORGANISM(S): Mus Musculus 
PXD028764 |
ProteomicsTRIM55 promotes noncanonical NF-kB signaling and B-cell-mediated immune responses by coordinating p100 ubiquitination and processing
The ubiquitination-dependent processing of NF-B2 (also known as p100) is a critical step in the activation of the noncanonical NF-B pathway. We investigated the molecular mechanisms regulating this process and showed that TRIM55 was the ubiquitin E3 ligase that mediated the ubiquitination of p100 ...
ORGANISM(S): Mus Musculus 
PXD044895 |
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