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We have performed the first systematic identification and analysis of intermediate size ncRNAs (50-500 nt) in the silkworm genome. We identified 194 novel ncRNAs, the expression profiles of them during the transitions from the egg to the first instar larva and from the fifth instar larva to the pupa...
ORGANISM(S): Bombyx mori 
Asymptomatic infection has become one of the biggest challenges in controlling the spread of COVID-19. However, the rapid diagnosis and pathogenesis elucidation of the disease remain critical issues. Here, we performed comprehensive lipidomic profiling of 267 serum samples from 89 asymptomatic COVID...
ORGANISM(S): Homo Sapiens 
2022-06-14 | PXD024410 |

Age-related Macular Degeneration (AMD) is a leading cause of incurable blindness in people over the age of 65. AMD is a late-onset multi-factorial neurodegenerative disease and its pathogenesis involves interaction of genetic and environmental factors. Several chromosomal regions have been as...

Cross-linking Mass Spectrometry (XL-MS) is a powerful tool for examining protein structures and interactions. Nevertheless, anal-ysis of low-abundance cross-linked peptides is often limited in data-dependent acquisition (DDA) mode due to its semistochastic nature. To address this issue, we introduce...
ORGANISM(S): Homo Sapiens Saccharomyces Cerevisiae 
2023-06-26 | PXD043282 |
We collected over 8000 mouse embryos of each developmental stage (zygote, 2-cell, 4-cell, 8-cell, morula, blastocyst) and performed tandem mass tag (TMT)-based quantitative mass spectrometry and identified nearly 5000 proteins for each stage. In-depth analysis indicates that protein expression profi...
ORGANISM(S): Mus Musculus (ncbitaxon:10090) 
2015-12-10 | MSV000079417 | MassIVE
Here, a workflow of 4D DIA proteomics by using the predicted multi-dimensional in silico library was established. A deep learning model Deep4D that could high-accurately predict the CCS and RT of both the unmodified and phosphorylated peptides was developed, which is the model based on self-attentio...
ORGANISM(S): Homo Sapiens Mus Musculus Saccharomyces Cerevisiae 
2023-04-19 | PXD034553 |
Bispecific-antibody therapy (BAT), the next strategy of immunotherapy for tumor patients, has showed the enhanced antitumor benefits than the monotherapy. Yet, few effective biomarkers were developed to monitor the response. Here, we investigated the first BAT longitudinal plasma proteome profiling ...
ORGANISM(S): Homo Sapiens 
2024-02-20 | PXD039260 |
Methylation profiling by EPIC microarray was performed on 3 human umbilical artery smooth muscle cells (HUASMCs) and human aortic smooth muscle cells (HAoSMCs) to assess CpG methylation in proximity to cardiovascular disease-associated variants.
ORGANISM(S): Homo sapiens 
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