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GenomicsDynamically reorganized chromatin is the key for the reprogramming of somatic cells to pluripotent cells
We investigated genome-wide nucleosome coverage and histone methylation occupancies in somatic MEFs, intermediate pre-iPSCs and fully reprogrammed iPSCs. We found that nucleosome occupancies increased in promoter regions and decreased in intergenic regions in pre-iPSCs and then recover to an interme...
ORGANISM(S): Mus musculus 
2015-12-13 | E-GEOD-60627 | biostudies-arrayexpress
UnknownBegonia guangdongensis, a new species of Begonia (Begoniaceae) from Guangdong, China.
Not available
S-EPMC7560510 | biostudies-literature
UnknownBis[2-(1,3-benzothia-zol-2-ylsulfan-yl)eth-yl] ether.
Not available
S-EPMC2980199 | biostudies-literature
TranscriptomicsNext Generation Sequencing Facilitates Quantitative Analysis of germ cell RA signaling mutant and control THY1+ spermatogonia Transcriptomes
Purpose: The goal of this sequencing is to investigate alterations in gene expression that result from impaired retinoid signaling compared with control, and how the RA signaling controls spermatogonia differentiation Methods: THY1+ spermatogonia mRNA profiles of 4-day-old control and germ cell spe...
ORGANISM(S): Mus musculus 
2016-04-04 | E-GEOD-79863 | biostudies-arrayexpress
MetabolomicsThe Formation of Phenol and Indole Flavor Substances in Stinky Tofu Brine Based on Metabolism of Aromatic Amino Acids

Understanding the formation mechanism of the flavor compounds in stinky tofu brine is crucial for controlling the flavor quality of Changsha stinky tofu. Dynamic changes in associated bacteria, enzymes, and differential metabolites in the metabolic pathway of aromatic amino acids in brine were in...

2026-03-20 | MTBLS2849 | MetaboLights
UnknownClinical implications of sequential MRD monitoring by NGS at 2 time points after chemotherapy in patients with AML.
Not available
S-EPMC8152512 | biostudies-literature
UnknownDysregulated immune and metabolic pathways are associated with poor survival in adult acute myeloid leukemia with CEBPA bZIP in-frame mutations.
Not available
S-EPMC10803338 | biostudies-literature
UnknownEsterase D stabilizes FKBP25 to suppress mTORC1.
Not available
S-EPMC8903700 | biostudies-literature
UnknownChemo-Enzymatic Strategy for the Efficient Synthesis of Steroidal Drugs with 10α-Methyl Group and a Side Chain at C17-Position from Biorenewable Phytosterols.
Not available
S-EPMC11040700 | biostudies-literature
UnknownPreserving low perfusion during surgical liver blood inflow control prevents hepatic microcirculatory dysfunction and irreversible hepatocyte injury in rats.
Not available
S-EPMC4585878 | biostudies-literature
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