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The purpose of this study is to investigate the transcriptional programs as it relates to disease latency initiated by different MLL fusion proteins, including: MLL-AF1p, MLL-AF6, MLL-Gas7, MLL-AF9 and MLL-ENL. Leukemia cell lines were established by transforming kit+ mouse bone marrow cells with re...
ORGANISM(S): Mus musculus 

The perturbations of the gut microbiota and metabolites are closely associated with the progression of inflammatory bowel disease (IBD). However, inconsistent findings across studies impede a comprehensive understanding of their roles in IBD and their potential as reliable diagnostic biomarkers. ...

2026-01-28 | MTBLS8713 | MetaboLights
The intrinsic regulation of PD-L1 expression remains unclear. Here we report that ZNF652 is a potent transcription repressor of PD-L1. ZNF652 frequently loses heterozygosity (LOH) in various cancers. Higher LOH rate and lack of estrogen-inducible transcription lead to suppressed expression of ZNF652...
ORGANISM(S): Homo Sapiens 
The polar filaments and polar tubes of Nosema bombycis were successfully purified by differential centrifugation, and the protein components were identified by proteomic methods, and the functions of these proteins were commented. These results will provide some reference value and significance for ...
ORGANISM(S): Nosema Bombycis Cq1 
Proteomics of Staphylococcus aureus SA113 after treatment with SX - 682
ORGANISM(S): Staphylococcus Aureus Subsp. Aureus Nctc 8325 
2025-12-31 | PXD072538 |
Azeliragon for the treatment of Staphylococcus aureus proteome
ORGANISM(S): Staphylococcus Aureus 
2025-10-27 | PXD069935 |
Our multi-omics analysis of local patients demonstrated significant distinctions compared to TCGA-THCA cohorts, highlighting the unique genetic characteristics of Chinese individuals with PTC. We identified novel biomarkers that hold potential for diagnosis and prognosis of PTC. Furthermore, develop...
ORGANISM(S): Homo Sapiens 
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