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TranscriptomicsComparing next-generation sequencing and microarray technologies in a toxicological study of the effects of aristolochic Acid on rat kidneys
RNA-Seq has been increasingly used for the quantification and characterization of transcriptomes. The ongoing development of the technology promises the more accurate measurement of gene expression. However, its benefits over widely accepted microarray technologies have not been adequately assessed,...
ORGANISM(S): Rattus norvegicus 
2012-02-02 | E-GEOD-21210 | biostudies-arrayexpress
ProteomicsNuclear HMGB1 is critical for CD8 T cell IFN-g production and anti-tumor immunity
HMGB1 has been extensively studied as a DAMP, with secreted cytokine function. However, its regulation on T cells, especially the function in the nucleus, has not been elucidated. Here, we extracted the total protein of CD8 T cells and enriched the proteins bound to HMGB1 through IP experiment. We...
ORGANISM(S): Mus Musculus 
2024-03-15 | PXD050639 |
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