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TranscriptomicsThe role of Ninjurin-1 deficiency in Jak2V617F clonal hematopoiesis mediated atherosclerosis plaque progression
Clonal haematopoiesis of indeterminate potential (CHIP) involves age-related acquisition and expansion of genes frequently mutated in haematologic malignancies (e.g. DNMT3A, TET2, or JAK2).  JAK2 heightens cardiovascular disease (CVD) risk. The mechanism, although incompletely understood, involves p...
ORGANISM(S): Mus musculus 
2025-12-22 | E-MTAB-16375 | biostudies-arrayexpress
UnknownAssociation of outdoor artificial light at night with myopia among Chinese adolescents: a representative cross-sectional study.
Not available
S-EPMC11466777 | biostudies-literature
TranscriptomicsMyeloid cells are enriched in tonsillar crypts providing insight into the host tropism of HPV
Viruses are the second leading cause of cancer worldwide, and human papillomavirus (HPV)-associated head and neck cancers are increasing in incidence in the United States. HPV preferentially infects the crypts of the tonsils rather than the surface epithelium. The present study sought to characteriz...
ORGANISM(S): Homo sapiens 
2021-06-18 | GSE155139 | GEO
UnknownSequentially bridged graphene sheets with high strength, toughness, and electrical conductivity.
Not available
S-EPMC6003513 | biostudies-literature
TranscriptomicsThe exon junction complex regulates the splicing of cell polarity gene dlg1 to control Wingless signaling in development
Wingless (Wg)/Wnt signaling is conserved in all metazoan animals and plays critical roles in development. The Wg/Wnt morphogen reception is essential for signal activation, whose activity is mediated through the receptor complex and a scaffold protein Dishevelled (Dsh). We report here that the exon ...
ORGANISM(S): Drosophila melanogaster 
2016-08-19 | E-GEOD-81220 | biostudies-arrayexpress
UnknownThalidomide Improves the Intestinal Mucosal Injury and Suppresses Mesenteric Angiogenesis and Vasodilatation by Down-Regulating Inflammasomes-Related Cascades in Cirrhotic Rats.
Not available
S-EPMC4731147 | biostudies-literature
UnknownArsenic Trioxide Consolidation Allows Anthracycline Dose Reduction for Pediatric Patients With Acute Promyelocytic Leukemia: Report From the Children's Oncology Group Phase III Historically Controlled Trial AAML0631.
Not available
S-EPMC5590801 | biostudies-literature
UnknownCD33 Splicing Polymorphism Determines Gemtuzumab Ozogamicin Response in De Novo Acute Myeloid Leukemia: Report From Randomized Phase III Children's Oncology Group Trial AAML0531.
Not available
S-EPMC5549451 | biostudies-literature
UnknownGlobal Cross-Sectional Study Evaluating the Attitudes towards a COVID-19 Vaccine in Pregnant and Postpartum Women.
Not available
S-EPMC9961540 | biostudies-literature
GenomicsInsights into GATA-1-Mediated Gene Activation versus Repression via Genome-wide Chromatin Occupancy Analysis
The transcription factor GATA-1 is required for terminal erythroid maturation and functions as an activator or repressor depending on gene context. Yet its in vivo site selectivity and ability to distinguish between activated versus repressed genes remain incompletely understood. In this study, we p...
ORGANISM(S): Mus musculus 
2009-11-25 | E-GEOD-16594 | biostudies-arrayexpress
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