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ProteomicsGMPS promoting tumor immune evasion by regulating the glycosylation modification of PD-L1
Hepatocellular carcinoma (HCC) is a malignant tumor characterized by rapid progression, whose development is attributed to severe immune evasion. Here, we conducted proteomic and scRNA-Seq analysis on advanced HCC tissues and identified a significant molecule, Guanine monophosphate synthase (GMPS). ...
ORGANISM(S): Mus musculus (Mouse) 
2026-05-25 | PXD045485 | Pride
Ptm Hcc Pd-l1 Immunotherapy 
UnknownMultiply doses of FDC of rosuvastatin and ezetimibe versus rosuvastatin monotherapy in Chinese patients with hypercholesterolemia (ROSE-CH): multicenter, randomized-controlled trial
Not available
S-EPMC12281852 | biostudies-literature
ProteomicsChemical Proteomics Profiling with an Indole Isocyanide Photoprobe
Chemoselective cysteine modification is pivotal for chemical biology and drug discovery. While photochemical strategies offer spatiotemporal control, most current methods rely on exogenous catalysts, complicating purification processes. Furthermore, the structural diversity of accessible conjugates ...
ORGANISM(S): Homo Sapiens 
2026-03-20 | PXD075923 |
ProteomicsDRUSP_A novel method of super-enhanced purification of ubiquitinome
A novel approach that combines Denatured-Refolded Ubiquitinated Sample Preparation (DRUSP) with a tandem hybrid specific UBD (ThUBD) for ubiquitinomic analysis.
ORGANISM(S): Mus Musculus 
PXD055428 |
ProteomicsProteomics and phosphoproteomics reveal dysregulated kinases and associated pathway in liver fibrosis
Liver fibrosis is the initial stage of most liver diseases, and it is also a pathological process involving the liver in the late stages of many metabolic diseases. Therefore, it is important to systematically understand the pathological mechanism of liver fibrosis and seek therapeutic approaches fo...
ORGANISM(S): Mus Musculus 
2025-01-16 | PXD059906 |
ProteomicsRNF128 aggravates metabolic dysfunction-associated steatotic liver disease progression via stabilization of SCD1
Background: Metabolic dysfunction–associated steatotic liver disease (MASLD) progresses from simple steatosis to metabolic dysfunction–associated steatohepatitis (MASH), yet its therapeutic development has been hampered by pathological complexity and heterogeneity. Methods: Bulk RNA-seq and diet-in...
ORGANISM(S): Mus Musculus 
PXD076845 |
UnknownRobust estimation of bacterial cell count from optical density.
Not available
S-EPMC7499192 | biostudies-literature
UnknownGlobal age-sex-specific all-cause mortality and life expectancy estimates for 204 countries and territories and 660 subnational locations, 1950-2023: a demographic analysis for the Global Burden of Disease Study 2023.
Not available
S-EPMC12535839 | biostudies-literature
UnknownGlobal burden of 292 causes of death in 204 countries and territories and 660 subnational locations, 1990-2023: a systematic analysis for the Global Burden of Disease Study 2023.
Not available
S-EPMC12535838 | biostudies-literature
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