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TranscriptomicsGenes induced by IFN-beta, IFN-gamma or unphosphoraylted STAT1 in human fibroblasts
A single high dose of IFN? activates powerful cellular responses in which many antiviral, pro-apoptotic, and anti-proliferative proteins are highly expressed. Since some of these proteins are deleterious, cells down-regulate this initial response rapidly. However, the expression of many antiviral ...
ORGANISM(S): Homo sapiens 
2013-09-18 | E-GEOD-50954 | biostudies-arrayexpress
TranscriptomicsTranscriptome analysis in macrophages isolated from wild-type, Stat1Y701F or Stat1-/- mice infected with Listeria monocytogenes for 6, 12, or 24 hours
We infected the bone marrow-derived macrophages (BMDM) isolated from WT, Stat1Y701F or Stat1-/- mice were infected with Listeria monocytogenes for 6, 12 or 24h, or left untreated in order to find out how the transcriptome of these genotypes differs during infection.
ORGANISM(S): Mus musculus 
2016-01-26 | E-MTAB-3598 | biostudies-arrayexpress
TranscriptomicsTranscriptome analysis in macrophages treated with type I interferon, heat-killed Listeria monocytogenes, or both.
To define the group of genes which is synergistically induced by cooperative activity of the type I interferon - activated Jak/STAT pathway and other pathways, we treated bone marrow-derived macrophages (BMDM) with heat-killed Listeria (hkL; non-STAT pathways activated), type I interferon alone (onl...
ORGANISM(S): Mus musculus 
2015-06-15 | E-MTAB-3015 | biostudies-arrayexpress
UnknownSuppressing PARylation by 2'-5'-oligoadenylate synthetase 1 inhibits DNA damage-induced cell death
Not available
S-SCDT-EMBOJ-2019-101573 | biostudies-other
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