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GenomicsPING 2.0: An R/Bioconductor package for nucleosome positioning using next-generation sequencing data
MNase-Seq and ChIP-Seq have evolved as popular techniques to study chromatin and histone modification. Although many tools have been developed to identify enriched regions, software tools for nucleosome positioning are still limited. We introduce a flexible and powerful open-source R package, PING 2...
ORGANISM(S): Saccharomyces cerevisiae 
2013-07-11 | E-GEOD-47073 | biostudies-arrayexpress
UnknownA network pharmacology-based approach to analyse potential targets of traditional herbal formulas: An example of Yu Ping Feng decoction.
Not available
S-EPMC6065326 | biostudies-literature
TranscriptomicsImatinib Treatment of GIST882
Gastrointestinal Stromal Tumor frequently harbor mutations in the KIT receptor tyrosine kinase and depend on its activity for growth. This underlies the efficacy of imatinib, a inhibitor of KIT activity, in GIST management. GIST882 is a patient derived GIST cell line that harbor a K640E exon 13 KIT ...
ORGANISM(S): Homo sapiens 
2010-10-13 | E-GEOD-22433 | biostudies-arrayexpress
TranscriptomicsETV1 knockdown in GIST cell lines
ETV1 is highly expressed in GIST cells and required for their survival and growth. To identify genes and pathways regulated by ETV1 in GIST, we performed expression profiles of GIST cells after ETV1 knockdown. Two GIST cell lines (GIST48 and GIST882) were infected in duplicate with three shRNA virus...
ORGANISM(S): Homo sapiens 
2010-10-13 | E-GEOD-19396 | biostudies-arrayexpress
GenomicsChIP-Seq of Histone H3K4me1 and H3K4me3 in human GIST48 cells
We previously mapped ETV1 using ChIP-Seq in GIST48 cells (GSE22441). Here, we map the enhancer landscape marked by histone H3K4me1 and the promoter landscape marked by histone H3K4me3 in GIST48 cells. Crosslink ChIP-Seq of H3K4me1 and H3K4me3 in GIST48 cells
ORGANISM(S): Homo sapiens 
2015-01-01 | E-GEOD-64609 | biostudies-arrayexpress
UnknownChallenges and Opportunities in Electrocatalytic CO2 Reduction to Chemicals and Fuels.
Not available
S-EPMC10091971 | biostudies-literature
TranscriptomicsRNA-Seq of murine GIST-like tumors after Etv1 ablation
We used a mouse expressing three alleles 1) KitV558Delta/+ activating allele that develop GIST-like tumors in the cecum, 2) Etv1 flox/flox conditional knockout allele and 3) Rosa26-CreERT2 tamoxifen activated Cre allele. Mice were treated with either Tamoxifen (to delete Etv1) or corn oil (control)....
ORGANISM(S): Mus musculus 
2015-01-01 | E-GEOD-64608 | biostudies-arrayexpress
GenomicsMapping of ETV1 genomic binding sites in gastrointestinal stromal tumor (GIST).
ETV1 is highly expressed in GIST and their presumed precursors--the interstitial cells of Cajal. ETV1 is required for survival for both GIST and ICC and regulates GIST signature genes. Here, using Illumina-Solexa based next-generation sequencing of ETV1 chromatin immunoprecipates (ChIP-Seq), we defi...
ORGANISM(S): Homo sapiens 
2010-10-14 | E-GEOD-22441 | biostudies-arrayexpress
UnknownAssociation of colorectal cancer susceptibility variants with esophageal cancer in a Chinese population.
Not available
S-EPMC4462730 | biostudies-literature
UnknownAn anti-passivation ink for the preparation of electrodes for use in electrochemical immunoassays.
Not available
S-EPMC6137421 | biostudies-literature
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