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UnknownKnockout of mouse Cyp3a gene enhances synthesis of cholesterol and bile acid in the liver.
Not available
S-EPMC3708357 | biostudies-literature
UnknownEfficient human-like antibody repertoire and hybridoma production in trans-chromosomic mice carrying megabase-sized human immunoglobulin loci.
Not available
S-EPMC8983744 | biostudies-literature
UnknownHumanized UGT2 and CYP3A transchromosomic rats for improved prediction of human drug metabolism.
Not available
S-EPMC6386724 | biostudies-literature
TranscriptomicsDe novo Assembly and Characterization of Swertia japonica Transcriptome for the Identification of Candidate Genes Involved in the Biosynthesis of Therapeutic Metabolites
Here, we performed deep transcriptome sequencing for the aerial-tissues and the roots of S. japonica, generating over 2 billion raw reads with an average length of 101 nt by using an Illumina paired-end sequencing by HiSeq2000 platform. Using a combined approach of three popular assemblers, de novo ...
ORGANISM(S): Swertia japonica 
2016-07-01 | E-GEOD-80057 | biostudies-arrayexpress
UnknownThalidomide-induced limb abnormalities in a humanized CYP3A mouse model.
Not available
S-EPMC4763305 | biostudies-literature
UnknownAging of spermatogonial stem cells by Jnk-mediated glycolysis activation.
Not available
S-EPMC6697785 | biostudies-literature
TranscriptomicsMicroarray analysis of gene expression under different light conditions
The size of tomato fruits are largely dependent on growth conditions. To obtain insights on how light intensity contributes to translocation from a leaf and a fruit, we developed a plant irradiation system based on light-emitting diodes (LEDs) to a leaf. By using this system, we investigated the cha...
ORGANISM(S): Solanum lycopersicum 
2012-05-01 | E-GEOD-35020 | biostudies-arrayexpress
UnknownCharacterization of human anti-EpCAM antibodies for developing an antibody-drug conjugate.
Not available
S-EPMC10015092 | biostudies-literature
UnknownReprogramming suppresses premature senescence phenotypes of Werner syndrome cells and maintains chromosomal stability over long-term culture.
Not available
S-EPMC4229309 | biostudies-literature
MetabolomicsDefective cytokinin signaling reprograms lipid and flavonoid gene-to-metabolite networks to mitigate high salinity in Arabidopsis

Cytokinin (CK) in plants regulates both developmental processes and adaptation to environmental stress. Arabidopsis histidine phosphotransfer ahp2,3,5 and type-B response regulator arr1,10,12 triple mutants are almost completely defective in CK signaling, and the ahp2,3,5

2021-11-25 | MTBLS2532 | MetaboLights
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