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MetabolomicsGut Microbiota Contributes to Heat Tolerance Through Metabolic Remodeling and Suppression of Thermogenesis in Chickens
Background The gut microbiota is increasingly recognized as a key regulator of host metabolic adaptation to environmental challenges. However, whether breed-specific gut microbiota contributes to variation in heat tolerance among poultry breeds remains unclear. This study used Cyan-shank partridge c...
2026-06-18 | MTBLS14785 | MetaboLights
MetabolomicsRelationships between digestive efficiency and metabolomic profiles of serum and intestinal contents in chickens
The increasing cost of conventional feedstuffs has bolstered interest in genetic selection for digestive efficiency (DE), a component of feed efficiency, assessed by apparent metabolisable energy corrected to zero nitrogen retention (AMEn). However, its measurement is time-consuming and constraining...
2018-05-02 | MTBLS560 | MetaboLights
MetabolomicsExploring the variations in intestinal microbial communities and metabolite profiles between heat-sensitive and heat-tolerant chickens through a comprehensive multi-omics approach

Heat stress (HS) compromises poultry health by disrupting intestinal integrity and microbiota homeostasis. This study compared heat stress-susceptible (HS-SUS) and heat stress-resistant (HS-RES) White Leghorn chickens under chronic cyclic HS (35±2°C, 8 h/day). HS-RES chickens demonstrated superio...

2025-09-12 | MTBLS12991 | MetaboLights
TranscriptomicsGene expression analysis of chickens (Gallus gallus) infected with recombinant influenza viruses
H5N1 subtype highly pathogenic avian influenza virus has been spreading to Asia, Eurasia and African coutries. An original or six of recombinant H5N1 subtype influenza viruses with varying survivability were infected to chickens for elucidating genes correlated with pathogenicity. Two chickens were ...
ORGANISM(S): Gallus gallus 
2012-03-30 | E-GEOD-32378 | biostudies-arrayexpress
TranscriptomicsTranscriptomic profiling of chicken adipose tissue of domestic chickens
Domestic chicken has been intensively studied because of its role as an efficient source of lean meat. However, commercial broilers resulting from genetic selection for rapid growth demonstrate detrimental traits, such as excess deposition of abdominal adipose tissue, metabolic disorders, and reduce...
ORGANISM(S): Gallus gallus 
2013-12-23 | E-GEOD-44394 | biostudies-arrayexpress
TranscriptomicsMolecular immunophenotyping of lungs and spleens in naive and vaccinated chickens early after pulmonary avian influenza A (H9N2) virus infection
In a respiratory-infection-model with the avian influenza A H9N2 virus, lung and splenic immune reactions in chickens were studied using a 5K chicken immuno-microarray. Groups of chickens were either mock-immunized (referred to as non-immune), vaccinated with inactivated viral antigen only (immune) ...
ORGANISM(S): Gallus gallus 
2015-11-02 | E-MTAB-3999 | biostudies-arrayexpress
TranscriptomicsTranscription profiling of jejunum from chickens with either a high or low natural antibody response which were fed an organic or conventially produced diet
ISA Brown Warren medium heavy layer hens were divergently selected for 25 generations on their primary immune response. Two selection chicken lines were established: chickens with a high natural antibody response (H) and chicken with a low natural antibody response (L). Besides a control line of ran...
ORGANISM(S): Gallus gallus 
2010-03-02 | E-MEXP-1798 | biostudies-arrayexpress
TranscriptomicsMicroRNA expression in chicken cecum following Campylobacter jejuni infection
SPF leghorn chickens were infected with C. jejuni. The cecum were collected at 8h post infection for total RNA isolation. The significantly expressed microRNAs between infected and non-infected chickens were identified through Solexa sequencing technology. Two libraries were made from each group, in...
ORGANISM(S): Gallus gallus 
2016-07-25 | E-GEOD-58767 | biostudies-arrayexpress
TranscriptomicsmRNA expression changes in chicken livers associated with field exposure to DDTs in KwaZulu-Natal, South Africa
Free-range chickens were sampled from homesteads in South Africa where DDT is sprayed for malaria control. The purpose was to detect potential effects associated with contamination. Livers were sampled post-mortem & analysed for DDTs (DDT and metabolites) contamination. Samples from two birds were f...
ORGANISM(S): Gallus gallus 
2018-10-16 | E-MTAB-7130 | biostudies-arrayexpress
Genomicschickens
chickens Metagenome
PRJNA428831 | ENA
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