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MetabolomicsRegulatory T cells promote endurance exercise adaptation by shielding muscle mitochondria from damage

Exercise enhances physical performance and reduces the risk of many disorders such as cardiovascular disease, type 2 diabetes, dementia and cancer. Exercise characteristically incites an inflammatory response, notably in skeletal muscles. While some effector mechanisms have been identified, regul...

2023-10-10 | MTBLS8391 | MetaboLights
UnknownBody fat distribution and bone mineral density in a multi-ethnic sample of postmenopausal women in The Malaysian Cohort.
Not available
S-EPMC11306509 | biostudies-literature
TranscriptomicsRegulatory T cell modulation by CBP/EP300 bromodomain inhibition [array]
Genome-wide gene expression changes in response to CBP inhibitor treatment in Treg cells using microarray. Expression profiling by microarray of Treg cells treated with DMSO or CBP inhibitor, and Th0 cells
ORGANISM(S): Homo sapiens 
2016-07-06 | E-GEOD-66596 | biostudies-arrayexpress
TranscriptomicsMicroarray based gene expression for invasive lobular cancer samples (RATHER)
As part of the RATHER (RAtional THERapy for breast cancer: individualized treatment for difficult-to-treat breast cancer subtypes) consortium, expression profiling of 144 untreated primary invasive lobular carcinoma (ILC) breast cancer tissues and 15 ILC cell lines was performed using microarray. Ge...
ORGANISM(S): Homo sapiens 
2016-01-05 | E-GEOD-68057 | biostudies-arrayexpress
TranscriptomicsWhole Genome Sequencing Informs Therapeutic Selection for Pancreatic Cancer
Pancreatic cancer remains one of the most lethal of malignancies and a major health burden. We performed whole genome sequencing and CNV analysis of 100 pancreatic ductal adenocarcinomas. Chromosomal rearrangements leading to gene disruption were frequent, affecting genes known to be important in pa...
ORGANISM(S): Homo sapiens 
2015-02-27 | E-GEOD-61502 | biostudies-arrayexpress
UnknownBCL11A is a triple-negative breast cancer gene with critical functions in stem and progenitor cells.
Not available
S-EPMC4338552 | biostudies-literature
UnknownA tumor DNA complex aberration index is an independent predictor of survival in breast and ovarian cancer.
Not available
S-EPMC4286124 | biostudies-literature
Genomics473655_dataset - samples
Exome and targeted amplicon sequencing data for tumor, germline and plasma samples from a patient with metastatic breast cancer.
EGAD00001002108 | EGA
GenomicsSequencing of serial plasma and multiregional tumor samples in a patient with metastatic breast cancer
Circulating tumor DNA analysis can be used to track tumor burden and analyze cancer genomes non-invasively but the extent to which it represents metastatic heterogeneity is unknown. Here, we follow a patient with metastatic ER and HER2 positive breast cancer receiving two lines of targeted therapy o...
EGAS00001001466 | EGA
GenomicsMurtaza-Rosenfeld-Caldas Data Access Committee
Data Access Committee EGAC00001000387
EGAC00001000387 | EGA
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