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UnknownEffects of Low versus High Glycemic Index Sugar-Sweetened Beverages on Postprandial Vasodilatation and Inactivity-Induced Impairment of Glucose Metabolism in Healthy Men.
Not available
S-EPMC5188457 | biostudies-literature
UnknownLong-Term Dietary Fish Meal Substitution with the Black Soldier Fly Larval Meal Modifies the Caecal Microbiota and Microbial Pathway in Laying Hens.
Not available
S-EPMC10451910 | biostudies-literature
UnknownCRISPR activation screen identifies BCL-2 proteins and B3GNT2 as drivers of cancer resistance to T cell-mediated cytotoxicity.
Not available
S-EPMC8956604 | biostudies-literature
ProteomicsA multi-parameter optimization in middle-down analysis of monoclonal antibodies by LC-MS/MS
In antibody-based drug research, regulatory agencies request a complete characterization of antibody proteoforms covering both the amino acid sequence and all post-translational modifications. The usual mass spectrometry-based approach to achieve this goal is bottom-up proteomics, which relies on th...
ORGANISM(S): Homo sapiens (Human) 
2023-03-15 | PXD038619 | Pride
Orbitrap ms Middle-down proteomics Monoclonal antibody Intact proteins Lc-ms/ms 
ProteomicsCRISPR activation screen identifies BCL-2 proteins and B3GNT2 as drivers of cancer resistance to T cell-mediated cytotoxicity
The cellular processes that govern tumor resistance to immunotherapy remain poorly understood. To gain insight into these processes, we perform a genome-scale CRISPR activation screen for genes that enable human melanoma cells to evade cytotoxic T cell killing. Overexpression of four top candidate g...
ORGANISM(S): Homo sapiens (Human) 
2022-02-09 | PXD031532 | Pride
Shotgun proteomics B3gnt2 Co-ip Melanoma 
TranscriptomicsMolecular characterization of the submergence response of Arabidopsis thaliana ecotype Columbia
This study profiles transcriptomic changes of Arabidopsis thaliana Col-0 in response to submergence. This dataset includes CEL files, RMA signal values and MAS5 P/M/A calls from total mRNA populations of plants at 9 to 10 leaf rosette stage. Biological replicates of root and shoot tissues were harve...
ORGANISM(S): Arabidopsis thaliana 
2010-11-12 | E-GEOD-24077 | biostudies-arrayexpress
UnknownEculizumab improves fatigue in refractory generalized myasthenia gravis.
Not available
S-EPMC6620379 | biostudies-literature
UnknownGenetic architecture of the inflammatory bowel diseases across East Asian and European ancestries.
Not available
S-EPMC10290755 | biostudies-literature
UnknownConsistent improvement with eculizumab across muscle groups in myasthenia gravis.
Not available
S-EPMC7448154 | biostudies-literature
UnknownLong-term safety and efficacy of eculizumab in generalized myasthenia gravis.
Not available
S-EPMC6619057 | biostudies-literature
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