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TranscriptomicsHuman iPSC-based model for Duchenne muscular dystrophy
We developed a novel somite-based step-wise strategy for the efficient derivation of functional human myocytes, suggesting that past failures were due to incomplete specification. Treatment with two small molecules inhibiting glycogen synthase kinase 3β (GSK-3β) and the Notch signaling pathway in ...
ORGANISM(S): Homo sapiens 
2016-06-16 | E-GEOD-70955 | biostudies-arrayexpress
UnknownCharacteristics and Potential Challenges of Digital-Based Interventions for Children and Young People: Scoping Review.
Not available
S-EPMC10148209 | biostudies-literature
UnknownRisk of Endometrial Cancer and Frequencies of Invasive Endometrial Procedures in Young Breast Cancer Survivors Treated With Tamoxifen: A Nationwide Study.
Not available
S-EPMC8209428 | biostudies-literature
TranscriptomicsComparing isogenic pairs of hESC and hiPSC lines reveals genetic background and reprogramming method as primary sources of transcriptional variation
The equivalency of human induced pluripotent stem cells (hiPSCs) with human embryonic stem cells (hESCs) remains controversial. Here, we devised a strategy to assess the contribution of clonal growth, reprogramming method and genetic background to transcriptional patterns in hESCs and hiPSCs. Surpri...
ORGANISM(S): Homo sapiens 
2015-10-26 | E-GEOD-73211 | biostudies-arrayexpress
TranscriptomicsRNAseq analyses of pathogenic Burkholderia glumae under in vitro and in vivo conditions
We analyzed B. glumae transcriptome from infected rice tissue using an RNAseq technique. To identify unique expression of B. glumae genes within rice tissues, we compared in vivo transcriptome data of B. glumae to in vitro data. To accomplish this, we analyzed differentially expressed genes (DEGs) a...
ORGANISM(S): Burkholderia glumae BGR1 
2014-08-21 | E-GEOD-56958 | biostudies-arrayexpress
UnknownThe Anabolic Response to Dietary Protein Is Not Limited by the Maximal Stimulation of Protein Synthesis in Healthy Older Adults: A Randomized Crossover Trial.
Not available
S-EPMC7693481 | biostudies-literature
UnknownMaladaptive neurovisceral interactions in patients with Internet gaming disorder: A study of heart rate variability and functional neural connectivity using the graph theory approach.
Not available
S-EPMC7317587 | biostudies-literature
UnknownIn silico and in vitro insights into tyrosinase inhibitors with a 2-thioxooxazoline-4-one template.
Not available
S-EPMC7753086 | biostudies-literature
TranscriptomicsTranscription profiling of mouse brain infected with prions in eight mouse-prion strain combinations in a systems approach to the study of prion disease
Prions cause transmissible neurodegenerative diseases and replicate by conformational conversion of normal, benign forms of prion protein (PrPC) to disease-causing PrPSc isoforms. A systems approach to disease postulates that disease arises from the pathological perturbation (genetic and/or environm...
ORGANISM(S): Mus musculus 
2009-03-25 | E-MTAB-76 | biostudies-arrayexpress
UnknownGlobal, regional, and national mortality among young people aged 10-24 years, 1950-2019: a systematic analysis for the Global Burden of Disease Study 2019.
Not available
S-EPMC8576274 | biostudies-literature
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