Sort   by:  
 Page size 
TranscriptomicsDo different neurons age differently? Direct genome-wide analysis of aging in single identified cholinergic neurons
The complexity of events associated with age-related memory loss (ARML) cannot be overestimated. The problem is further complicated by the enormous diversity of neurons in the CNS and even synapses of one neuron within a neural circuit. Large-scale single-neuron analysis is not only challenging but ...
ORGANISM(S): Aplysia californica 
2010-05-20 | E-GEOD-18783 | biostudies-arrayexpress
GenomicsStress regulation of sustained attention and the cholinergic attention system
Stress regulation of sustained attention and the cholinergic attention system
PRJNA619064 | ENA
TranscriptomicsGenome-wide expression analysis of human fibroblasts and converted neurons
Human fibroblasts can be directly converted into cholinergic neurons by Neurogenin 2 (Neurog2 or NGN2) under the treatments of small molecules. Genome-wide analysis of gene expression was performed to examine the similarity of converted neurons to samples from human brain or spinal cord. Total RNA o...
ORGANISM(S): Homo sapiens 
2014-01-16 | E-GEOD-45954 | biostudies-arrayexpress
GenomicsDrosophila Cholinergic Neurons
Drosophila Cholinergic Neurons
PRJNA87141 | ENA
UnknownThe Cholinergic System as a Treatment Target for Opioid Use Disorder.
Not available
S-EPMC6314885 | biostudies-literature
TranscriptomicsStress regulation of sustained attention and the cholinergic attention system
Background: Stress exacerbates symptoms of schizophrenia and attention deficit hyperactivity disorder, which are characterized by impairments in sustained attention. Yet how stress regulates attention remains largely unexplored. Here we investigated whether a 6-day variable stressor (VS) altered sus...
ORGANISM(S): Rattus norvegicus 
2020-05-01 | GSE147806 | GEO
TranscriptomicsExpression data from naM-CM-/ve and MPTP-exposed cholinergic transgenic mice
PD is the second most common neurodegenerative disease worldwide with growing prevalence. MPTP is a neurotoxin which causes the appearance of Parkinson's disease (PD) pathology. The involvement of the cholinergic system in PD has been identified decades ago and anti-cholinergic drugs were upon the...
ORGANISM(S): Mus musculus 
2012-01-09 | E-GEOD-31458 | biostudies-arrayexpress
TranscriptomicsTranscription profiling of C. elegans specific cells from the nervous system.
Background: With its fully sequenced genome and simple, well-defined nervous system, the nematode C. elegans offers a unique opportunity to correlate gene expression with neuronal differentiation. The lineal origin, cellular morphology and synaptic connectivity of each of the 302 neurons are known....
ORGANISM(S): Caenorhabditis elegans 
2008-06-15 | E-GEOD-8004 | biostudies-arrayexpress
UnknownCholinergic system changes in Parkinson's disease: emerging therapeutic approaches.
Not available
S-EPMC8985079 | biostudies-literature
UnknownCholinergic System and Its Therapeutic Importance in Inflammation and Autoimmunity.
Not available
S-EPMC8082108 | biostudies-literature
Sort   by:  
 Page size