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TranscriptomicsGene expression data from lateral ventricle choroid plexuses of developing and adult rats
Choroid plexuses (CP) develop early during development. They form a barrier between the blood and the cerebrospinal fluid, and fulfill important protective and nutritive functions. We used Affymetrix microarrays to assess whether CP of the lateral ventricles (LVCP) have similar functions in developi...
ORGANISM(S): Rattus norvegicus 
2013-09-17 | E-GEOD-44056 | biostudies-arrayexpress
ProteomicsExtracellular vesicles derived from the choroid plexus trigger neural stem cells differentiation
An organized network of beating cilia transports cerebrospinal fluid (CSF) through the ventricles of the brain. CSF takes along diverse solutes including extracellular vesicles (EV), which arise from the choroid plexus, a secretory epithelium that reaches into the ventricles. Along their path throug...
ORGANISM(S): Mus musculus (Mouse) Rattus norvegicus (Rat) 
2022-12-18 | PXD031862 | Pride
Cerebrospinal fluid Neural stem cells Mass spectrometry Extracellular vesicles Exosome assay Neural stem cell differentiation Choroid plexus derived vesicle 
ProteomicsImportance of choroid plexus-mediated extracellular vesicle secretion in the pathogenesis of Alzheimer’s disease
Alzheimer’s disease (AD) is a major neurodegenerative disease characterized by extracellular amyloid β (Aβ) plaques and intracellular hyperphosphorylated tau (P-tau). Increasing evidence indicates that extracellular vesicles (EVs) play an important role in AD pathogenesis. We previously reported tha...
ORGANISM(S): Mus musculus (Mouse) 
2021-09-09 | PXD021665 | Pride
Ev Choroid plexus Csf Alzheimer Aβo 
UnknownChoroid plexus extracellular vesicle transport of blood-borne insulin-like growth factor 1 to the hippocampus of the immature brain.
Not available
S-EPMC11630522 | biostudies-literature
UnknownImportance of extracellular vesicle secretion at the blood-cerebrospinal fluid interface in the pathogenesis of Alzheimer's disease.
Not available
S-EPMC8381545 | biostudies-literature
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