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UnknownInterleukin-17-dependent autoimmunity to collagen type V in atherosclerosis.
Not available
S-EPMC3010213 | biostudies-literature
TranscriptomicsHypothalamic transcriptome plasticity in two rodent species reveals divergent differential gene expression but conserved pathways
We have addressed the question of how different rodent species cope with the life-threatening homeostatic challenge of dehydration at the level of transcriptome modulation in the supraoptic nucleus (SON), a specialised hypothalamic neurosecretory apparatus responsible for the production of the antid...
ORGANISM(S): Mus musculus 
2010-11-29 | E-GEOD-25574 | biostudies-arrayexpress
ProteomicsProteomics and phosphoproteomics of the diurnal cycle in chow and high fat high sucrose feed rats
There is growing evidence that energy metabolism and insulin action are regulated by mechanisms that follow a diurnal rhythm and it has been proposed that defects in Akt signalling are associated with the pathophysiology of metabolic disease. It is therefore important to investigate these parameters...
ORGANISM(S): Rattus norvegicus (Rat) 
2019-05-20 | PXD010242 | Pride
Insulin signaling High fat high sucrose diet Phosphoproteomics 
ProteomicsRat Liver HFD vs Chow, HFD vs PKCepsilon ASO
Insulin resistance drives the development of type 2 diabetes (T2D). In liver, diacylglycerol (DAG) is a key mediator of lipid-induced insulin resistance. DAG activates protein kinase C epsilon (PKCε), which phosphorylates and inhibits the insulin receptor. In rats, a 3-day high fat diet produces he...
ORGANISM(S): Rattus norvegicus (Rat) 
2018-08-30 | PXD010209 | Pride
Rat liver Insulin resistance 
UnknownIntermittent access to preferred food reduces the reinforcing efficacy of chow in rats.
Not available
S-EPMC2576087 | biostudies-literature
UnknownMolecular Identification of Mid to Final Stage Slipper Lobster Phyllosoma Larvae of the Genus Chelarctus (Crustacea: Decapoda: Scyllaridae) Collected in the Pacific with Descriptions of Their Larval Morphology.
Not available
S-EPMC9169114 | biostudies-literature
TranscriptomicsGene expression changes in aortas of mice on high fat versus regular chow diet.
To determine effects of hyperglycemia and insulin resistance on arterial wall biology, gene expression profiles were generated using aortas from mice on high fat (35% fat) diet and their respective non diabetic regular chow fed controls. Keywords: Chip Experiment was done in triplicate with three in...
ORGANISM(S): Mus musculus 
2011-12-23 | E-GEOD-6735 | biostudies-arrayexpress
TranscriptomicsCircadian Liver Gene Expression in Animals on Normal Chow or High Fat Diet
Circadian and metabolic processes are codependent. This experiment was designed to understand how a high fat diet affects circadian gene expression in the liver. Circadian gene expression in the liver is necessary for energy balance. Animals consuming normal chow or high fat diet (60% kcal from fat)...
ORGANISM(S): Mus musculus 
2013-12-19 | E-GEOD-52333 | biostudies-arrayexpress
UnknownWall shear stress analysis using 17.6 Tesla MRI: A longitudinal study in ApoE-/- mice with histological analysis.
Not available
S-EPMC7454980 | biostudies-literature
ProteomicsMurine Liver tissue on high fat diet
Younger age and obesity increase the incidence and rates of metastasis of triple-negative breast cancer (TNBC), an aggressive subtype of breast cancer. The tissue microenvironment, specifically the extracellular matrix (ECM), is known to promote tumor invasion and metastasis. We sought to characteri...
ORGANISM(S): Mus musculus (Mouse) 
2024-06-06 | PXD051409 | Pride
Obesity Liver Murine High-fat diet 
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