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TranscriptomicsComparative genomic hybridization of human nasal NK/T-cell Lymphoma (8 tumor samples, 2 cell lines)
A ﾑCartes dﾒIdentite des Tumeursﾒ (CIT) project from the french Ligue Nationale Contre le Cancer (http://cit.ligue-cancer.net ) | Human genome-wide CIT-aCGH-V6-4.4K : 8 NKTCL biopsies, 2 NKTCL cell lines. Biopsies and cell lines of NK/T-cell lymphoma, nasal-type (NKTCL) were subject to combine...
ORGANISM(S): Homo sapiens 
2009-12-31 | E-TABM-791 | biostudies-arrayexpress
TranscriptomicsGenome-wide transcription analysis of Escherichia coli in response to extremely low-frequency magnetic fields
The widespread use of electricity raises the question of whether or not 50 Hz (power line frequency in Europe) magnetic fields (MFs) affect organisms. We investigated the transcription of Escherichia coli K-12 MG1655 in response to extremely low-frequency (ELF) MFs. Fields generated by three signal ...
ORGANISM(S): Escherichia coli str. K-12 substr. MG1655 
2012-01-28 | E-GEOD-35371 | biostudies-arrayexpress
TranscriptomicsAmplification and overexpression of vinculin are associated with increased tumor cell proliferation and progression in advanced prostate cancer
We analyzed the 10q22 amplification in advanced prostate cancer and subjected the genes located in the common amplified region to an RNAi screen. We found vinculin as the most promising candidate gene and analyzed its protein expression on more than 400 prostate cancers by using the tissue micrarray...
ORGANISM(S): Homo sapiens 
2011-02-08 | E-GEOD-24216 | biostudies-arrayexpress
TranscriptomicsThe bromodomain protein BRD4 regulates splicing during heat shock
During heat stress cyto-protective genes including heat shock proteins are transcriptionally up-regulated and post-transcriptional splicing is inhibited. In contrast, co-transcriptional mRNA-splicing is maintained. These factors closely resemble the proteotoxic stress response during tumor developme...
ORGANISM(S): Homo sapiens 
2016-09-07 | E-GEOD-73471 | biostudies-arrayexpress
Genomicsena-DATASET-DKFZ-24-12-2020-10:12:59:494-197 - samples
In Coronavirus Disease 2019 (COVID-19), hypertension and cardiovascular diseases are major risk factors for critical disease progression. However, the underlying reasons and the effect of the main anti-hypertensive therapies—angiotensin-converting enzyme inhibitors (ACEIs) and angiotensin recep...
EGAD00001006828 | EGA
2019 novel coronavirus infection 2019-nCoV infection coronavirus disease 2019 COVID-19 SARS-coronavirus 2 SARS-CoV-2 severe acute respiratory syndrome coronavirus 2 
GenomicsHypertension delays viral clearance and exacerbates airway hyperinflammation in patients with COVID-19
In coronavirus disease 2019 (COVID-19), hypertension and cardiovascular diseases are major risk factors for critical disease progression. However, the underlying causes and the effects of the main anti-hypertensive therapies-angiotensin-converting enzyme inhibitors (ACEIs) and angiotensin receptor b...
EGAS00001004772 | EGA
2019 novel coronavirus infection 2019-nCoV infection coronavirus disease 2019 COVID-19 SARS-coronavirus 2 SARS-CoV-2 severe acute respiratory syndrome coronavirus 2 
TranscriptomicsHigh-throughput sequencing of matched colorectal normal, tumor and metastasis tissues and proof-of principal bioinformatics modeling of therapeutic consequences of miRNA applications
MiRNAs are discussed as diagnostic and therapeutic molecules. However, effective miRNA drug treatments with miRNAs are so far hampered by the complexity of the miRNA networks. To identify potential miRNA drugs in colorectal cancer, we profiled miRNA and mRNA expression in matching normal, tumor and ...
ORGANISM(S): Homo sapiens 
2013-09-18 | E-GEOD-46622 | biostudies-arrayexpress
UnknownA cross-disease meta-GWAS identifies four new susceptibility loci shared between systemic sclerosis and Crohn's disease.
Not available
S-EPMC7002703 | biostudies-literature
UnknownObesity, metabolic factors and risk of different histological types of lung cancer: A Mendelian randomization study.
Not available
S-EPMC5464539 | biostudies-literature
GenomicsComprehensive genomic profiles of small cell lung cancer
We have sequenced the genomes of 110 small cell lung cancers (SCLC), one of the deadliest human cancers. We found bi-allelic inactivation of TP53 and RB1 in nearly all the tumors analyzed, sometimes by complex genomic rearrangements. Two tumors with wild-type RB1 had evidence of chromothripsis leadi...
EGAS00001000925 | EGA
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