Chromatin remodeling complex

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1 Hudson Institute of Medical Research, Clayton, VIC, Australia, 2 Department of Molecular and Translational Sciences, Monash University, Clayton, VIC, Australia (1)
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IDH1 Reprograms Nucleotide Metabolism by Inducing Chromatin Remodeling and DHODH Transcription to Drive Chemoresistance in Nasopharyngeal Carcinoma

Metabolic reprogramming under therapeutic stress may represent a targetable vulnerability for cancer treatment. Elucidation of the metabolic alterations linked to chemotherapy in nasopharyngeal carcinoma (NPC) could uncover potential therapeutic strategies. Using proteomics and transcriptomic pro...

2026-01-14 | MTBLS11531 | MetaboLights

Involvement of a chromatin remodeling complex in damage tolerance during DNA replication

ATP-dependent chromatin remodeling complexes have been shown to participate in DNA replication in addition to transcription and DNA repair. However, the mechanisms of their involvement in DNA replication remain unclear. Here, we reveal a specific function of the yeast INO80 chromatin remodeling comp...

ORGANISM(S): Saccharomyces cerevisiae

2010-06-20 | E-GEOD-18570 | biostudies-arrayexpress

Ino80 chromatin remodeling complex promotes recovery of stalled replication forks

This SuperSeries is composed of the following subset Series: GSE9233: Genome-wide localization of Ino80 and Arp5 on chromosome in Saccharomyces cerevisiae GSE9420: Genome-wide localization of Ino80 on chromosome in Saccharomyces cerevisiae Keywords: SuperSeries Refer to individual Series

ORGANISM(S): Saccharomyces cerevisiae

2008-04-10 | E-GEOD-9421 | biostudies-arrayexpress

A SWI/SNF nucleosome remodeling complex acts in non-coding RNA-mediated transcriptional silencing

RNA-mediated transcriptional silencing prevents deleterious effects of transposon activity and controls the expression of protein-coding genes. It involves long non-coding RNAs (lncRNAs)1, which in Arabidopsis thaliana are produced by a specialized RNA Polymerase V (Pol V)2. lncRNAs guide Argonaute-...

ORGANISM(S): Arabidopsis thaliana

2012-12-01 | E-GEOD-38400 | biostudies-arrayexpress

Genome-wide profile of the SWI/SNF chromatin remodeling complex

A systems understanding of nuclear organization and events is critical for determining how cells divide, differentiate and respond to stimuli and for identifying the causes of diseases. Chromatin remodeling complexes such as SWI/SNF have been implicated in a wide variety of cellular processes includ...

ORGANISM(S): Homo sapiens

2011-01-10 | E-GEOD-24397 | biostudies-arrayexpress

Genome-wide localization of Ino80 on chromosome in Saccharomyces cerevisiae

Background: Chromatin remodeling complexes facilitate the access of enzymes that mediate transcription, replication or repair of DNA by modulating nucleosome position and/or composition. Ino80 is the DNA-dependent Snf2-like ATPase subunit of a complex whose nucleosome remodeling activity requires ac...

ORGANISM(S): Saccharomyces cerevisiae

2008-04-10 | E-GEOD-9420 | biostudies-arrayexpress

Histone H2B ubiquitylation represses gametogenesis by opposing RSC-Dependent chromatin remodeling at the ste11 master regulator locus

Chromatin modifications play a pivotal role in cell fate decision. In fission yeast, the ste11 gene encodes the master regulator initiating the switch from vegetative growth to gametogenesis when cells starve. The methylation of H3K4 by Set1-COMPASS and consequent promoter nucleosome deacetylation w...

ORGANISM(S): Schizosaccharomyces pombe

2016-07-22 | E-GEOD-80524 | biostudies-arrayexpress

Genome-wide localization of Ino80 and Arp5 on chromosome in Saccharomyces cerevisiae

ORGANISM(S): Saccharomyces cerevisiae

2008-04-10 | E-GEOD-9233 | biostudies-arrayexpress

Diet-induced chromatin remodeling in mice livers

The tissue-specific packaging of the genome into the nucleus through chromatin is fundamentally involved in gene regulation, and aberrant modifications to chromatin are a hallmark of many diseases. We show here that a high fat (HF) diet leads to substantial chromatin remodeling in the livers of C57B...

ORGANISM(S): Mus musculus

2014-07-17 | E-GEOD-55581 | biostudies-arrayexpress

Harnessing of the Nucleosome Remodeling Deacetylase complex controls lymphocyte development and prevents leukemogenesis

Cell fate decisions depend on the interplay between chromatin regulators and transcription factors. Here we show that activity of the Mi-2u Nucleosome Remodeling and Deacetylase (NuRD) complex is controlled by the Ikaros family of lymphoid-lineage determining proteins. Ikaros, an integral component ...

ORGANISM(S): Mus musculus

2011-11-13 | E-GEOD-32311 | biostudies-arrayexpress

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