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TranscriptomicsSex-dependent and -independent X-chromosome histone modifications in Drosophila melanogaster
Drosophila X chromosomes are subject to dosage compensation in males and are known to have a specialized chromatin structure in the male soma. We are interested in how specific chromatin structure change contributes to X chromosome hyperactivity and dosage compensation. We have conducted a global a...
ORGANISM(S): Drosophila melanogaster 
2010-01-11 | E-GEOD-15593 | biostudies-arrayexpress
GenomicsChromatin Structure and Gene Expression Programs of Human Embryonic and Induced Pluripotent Stem Cells
This SuperSeries is composed of the following subset Series: GSE23402: Chromatin Structure and Gene Expression Programs of Human Embryonic and Induced Pluripotent Stem Cells (Affymetrix) GSE23455: Chromatin Structure and Gene Expression Programs of Human Embryonic and Induced Pluripotent Stem Cells ...
ORGANISM(S): Homo sapiens 
2010-08-08 | E-GEOD-22499 | biostudies-arrayexpress
TranscriptomicsControl of chromatin structure by Spt6 has different consequences in coding and regulatory regions
Spt6 is a highly conserved factor that carries out important functions in transcription and chromatin structure. To gain new insights into Spt6, we measured nucleosome occupancy along Saccharomyces cerevisiae chromosome III in an spt6 mutant and found that the level of nucleosomes is greatly reduced...
ORGANISM(S): Saccharomyces cerevisiae 
2010-12-01 | E-GEOD-21787 | biostudies-arrayexpress
GenomicsDivergent residues within histone H3 define a unique chromatin structure in S. cerevisiae
Histones are among the most conserved proteins known, but organismal differences do exist. In this study we examined the contribution that divergent amino acids within histone H3 make to cell growth and chromatin structure in S. cerevisiae. We show that, while amino acids that define histone H3.3 ar...
ORGANISM(S): Saccharomyces cerevisiae 
2015-11-10 | E-GEOD-73425 | biostudies-arrayexpress
GenomicsChromatin Structure and Gene Expression Programs of Human Embryonic and Induced Pluripotent Stem Cells (ChIP-seq)
Knowledge of both the global chromatin structure and the gene expression programs of human embryonic stem (ES) cells and induced pluripotent stem (iPS) cells should provide a robust means to assess whether the genomes of these cells have similar pluripotent states. Recent studies have suggested tha...
ORGANISM(S): Homo sapiens 
2010-08-09 | E-GEOD-23455 | biostudies-arrayexpress
GenomicsDynamic alterations of 3D chromatin structure during differentiation
Regulation of gene expression underlies the establishment and maintenance of cell identity. Chromatin structure and gene activity are linked at long-range via positioning of loci to transcriptionally permissive (euchromatin) or repressive (heterochromatin) environments and at short-range by connecti...
ORGANISM(S): Mus musculus 
2019-08-27 | E-MTAB-2063 | biostudies-arrayexpress
TranscriptomicsChromatin Structure and Gene Expression Programs of Human Embryonic and Induced Pluripotent Stem Cells (Affymetrix)
Knowledge of both the global chromatin structure and the gene expression programs of human embryonic stem (ES) cells and induced pluripotent stem (iPS) cells should provide a robust means to assess whether the genomes of these cells have similar pluripotent states. Recent studies have suggested tha...
ORGANISM(S): Homo sapiens 
2010-08-09 | E-GEOD-23402 | biostudies-arrayexpress
ProteomicsIntricate structure of the interphase chromocenter revealed by the analysis of a factor involved in species formation
In higher eukaryotes centromeres often coalesce into a large intranuclear domain called the chromocenter. Chromocenters are important for the organization of pericentric heterochromatin and a disturbance of their formation results in an upregulation of repetitive elements and causes defects in chrom...
ORGANISM(S): Drosophila melanogaster (Fruit fly) 
2020-03-23 | PXD012551 | Pride
Chromatin proteomics Drosophila Chromocenter Centromeres 
TranscriptomicsDynamic alterations of 3D chromatin structure during differentiation RNA-seq
Regulation of gene expression underlies the establishment and maintenance of cell identity. Chromatin structure and gene activity are linked at long-range via positioning of loci to transcriptionally permissive (euchromatin) or repressive (heterochromatin) environments and at short-range by connecti...
ORGANISM(S): Mus musculus 
2019-08-27 | E-MTAB-2125 | biostudies-arrayexpress
UnknownChromatin structure related to oncogenesis.
Not available
S-EPMC10394151 | biostudies-literature
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