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ProteomicsEnamel peptide analysis to determine chromosomal sex of human remains (kōiwi tangata) of Māori-era individuals from New Zealand (Aotearoa)
Amelogenin, a protein involved in the formation of enamel occurs as two isoforms, AMEL X and AMEL Y, which are encoded on the X and Y chromosome respectively. Isoform-specific peptides can be used for the determination of the chromosomal sex in ancient teeth. This strategy was used here to determine...
ORGANISM(S): Homo sapiens (Human) 
2026-01-14 | PXD065222 | Pride
Chromosomal sex determination of human remains Amilogenin 
ProteomicsProteomic sex determination vs osteological sex estimation – what effect do our techniques have on the way we view the people of the past?
Amelogenin, a protein involved in the formation of enamel occurs as two isoforms, AMEL X and AMEL Y, which are encoded on the X and Y chromosome respectively. Isoform-specific peptides can be used for the determination of the chromosomal sex in ancient teeth. This strategy was used to determine the ...
ORGANISM(S): Homo sapiens (Human) 
2025-11-25 | PXD066946 | Pride
Chromosomal sex determination Amel y Amel x Amelogenin 
TranscriptomicsUncoupling X chromosome number from sex determination separates contribution of sex and X dose to sex-biased gene expression in C. elegans
The difference in X chromosome copy number creates a potential difference in X chromosomal gene expression between males and females. In many animals, dosage compensation mechanisms equalize X chromosome expression between sexes. Yet, X chromosome is also enriched for sex-biased genes due to differe...
ORGANISM(S): Caenorhabditis elegans 
2016-04-06 | E-GEOD-77794 | biostudies-arrayexpress
UnknownGenetic identification of putative remains of the famous astronomer Nicolaus Copernicus.
Not available
S-EPMC2718376 | biostudies-literature
TranscriptomicsGenome wide analysis reveals association of a FTO gene variant with epigenetic changes of several genes in human blood
FTO gene variants show the strongest association to obesity so far, but the role of the gene in obesity remains unclear. The FTO protein is a demethylation enzyme, which suggests that the link to obesity could be mediated through epigenetic changes. Herein, we determine the genome wide DNA methylati...
ORGANISM(S): Homo sapiens 
2012-01-10 | E-GEOD-27860 | biostudies-arrayexpress
UnknownPhysical Mapping and Refinement of the Painted Turtle Genome (Chrysemys picta) Inform Amniote Genome Evolution and Challenge Turtle-Bird Chromosomal Conservation.
Not available
S-EPMC4524486 | biostudies-literature
TranscriptomicsAutosomal Dosage Compensation in Aneuploidy and Cancer Is Mediated by Transcriptional Bursting Regulation (bulk RNA-Seq)
Aneuploidy, resulting from partial (segmental) or complete chromosomal gains or losses, is generally detrimental to organismal fitness, but is also associated with tumorigenicity. While sex chromosome aneuploidies are well-tolerated via dedicated allelic dosage compensation mechanisms, the existence...
ORGANISM(S): Mus musculus 
2026-10-02 | E-MTAB-15633 | biostudies-arrayexpress
TranscriptomicsChromatin immunoprecipitation of the MSL-1 and MSL-3 vs a mock IP in Drosophila and transcription profiling of X linked genes in WT male or female III instar larvae to provide X chromosome wide profiling of MSL-1 distribution and dosage compensation in Drosophila
Dosage compensation ensures that males and females, despite unequal number of X chromosomes, equalize for X linked gene expression. In Drosophila, it is achieved by a two-fold up-regulation of most of the genes present on the male X chromosome, and requires the association of the Dosage Compensation...
ORGANISM(S): Drosophila melanogaster 
2006-04-01 | E-MEXP-554 | biostudies-arrayexpress
GenomicsSolexa.H3K9me2_antibody2.S2
modENCODE_submission_3953 This submission comes from a modENCODE project of Gary Karpen. For full list of modENCODE projects, see http://www.genome.gov/26524648 Project Goal: We aim to determine the locations of the major histone modifications across the Drosophila melanogaster genome. The modificat...
ORGANISM(S): Drosophila melanogaster 
2013-05-28 | E-GEOD-47229 | biostudies-arrayexpress
TranscriptomicsAutosomal Dosage Compensation in Aneuploidy and Cancer Is Mediated by Transcriptional Bursting Regulation (Xpress-seq scRNA-seq)
Aneuploidy, resulting from partial (segmental) or complete chromosomal gains or losses, is generally detrimental to organismal fitness, but is also associated with tumorigenicity. While sex chromosome aneuploidies are well-tolerated via dedicated allelic dosage compensation mechanisms, the existence...
ORGANISM(S): Mus musculus 
2026-10-02 | E-MTAB-15744 | biostudies-arrayexpress
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