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Genomics
Chron fermentation
PRJNA1160072 | ENA
ProteomicsThe Gut Microbiota Metabolite Succinate promotes Adipose Tissue Browning in Crohn’s Disease
In Crohn’s disease (CD), microbe-host interactions are altered, with changes in microbial’s communities and barrier defects leading to translocation of microbes to surrounding adipose tissue (AT). We evaluated the presence of beige AT depots in CD and questioned whether succinate and/or bacterial tr...
ORGANISM(S): Homo sapiens (Human) 
2022-09-14 | PXD030520 | Pride
Chron disease Microbiota Proteomics 
UnknownAcute paracoccidioidomycosis worsened by immunosuppressive therapy due to a misdiagnosis of Crohn's disease.
Not available
S-EPMC9870162 | biostudies-literature
UnknownMeasurement error correction for the cumulative average model in the survival analysis of nutritional data: application to Nurses' Health Study.
Not available
S-EPMC2809827 | biostudies-literature
TranscriptomicsExpression data from livers of high fat fed rats treated with ACC inhibitor PF-04923503
Fundamental alterations in lipid metabolism including increased rates of de novo lipogenesis (DNL), reduced fatty acid oxidation (FAOX) and ectopic lipid accumulation in skeletal muscle and liver are characteristic of type 2 diabetes mellitus (T2DM) and have been hypothesized to directly contribute ...
ORGANISM(S): Rattus norvegicus 
2011-06-30 | E-GEOD-28058 | biostudies-arrayexpress
UnknownAcrAB efflux pump impacts on the survival of adherent-invasive Escherichia coli strain LF82 inside macrophages.
Not available
S-EPMC9931695 | biostudies-literature
UnknownThe ability of an attaching and effacing pathogen to trigger localized actin assembly contributes to virulence by promoting mucosal attachment.
Not available
S-EPMC4146666 | biostudies-literature
TranscriptomicsGenome wide dissection of the quorum sensing signalling pathway in Trypanosoma brucei
The protozoan parasites Trypanosoma brucei spp. are responsible for important human and livestock diseases in sub Saharan Africa. In the mammalian blood, two developmental forms of the parasite exist: proliferative ?slender? forms and transmissible ?stumpy? forms that are quiescent, awaiting uptake ...
ORGANISM(S): Trypanosoma brucei brucei 
2013-12-16 | E-GEOD-46501 | biostudies-arrayexpress
TranscriptomicsHepatitis C Virus Infection Activates a Novel Innate Pathway Involving IKKα in Lipogenesis and Viral Assembly
Hepatitis C virus interacts extensively with host factors not only to establish productive infection but also to trigger unique pathological processes. Our recent genome-wide siRNA screen demonstrated that IKKα is a critical host factor for HCV. Here we describe a novel NF-κB-independent and kinase-...
ORGANISM(S): Homo sapiens 
2013-05-08 | E-GEOD-46528 | biostudies-arrayexpress
TranscriptomicsInterferon Lambda Alleles Predict Innate Antiviral Immune Responses and Hepatitis C Virus Permissiveness.
Hepatitis C virus (HCV) infection can result in viral chronicity or clearance. Although host genetics and particularly genetic variation in the interferon lambda (IFNL) locus are associated with spontaneous HCV clearance and treatment success, the mechanisms guiding these clinical outcomes remain un...
ORGANISM(S): Homo sapiens 
2014-02-12 | E-GEOD-54648 | biostudies-arrayexpress
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