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MetabolomicsRelationship Between Vitamin D Levels and Psychological Stress-Induced Asthma Prevalence: An Untargeted Metabolomics Study Combined with the NHANES Database
The incidence of psychological stress–induced asthma has been increasing annually, and numerous previous studies have shown that vitamin D is associated with the development of asthma as well as anxiety and depression. However, no studies to date have clarified the relationship between vitamin D and...
2026-04-16 | MTBLS14208 | MetaboLights
TranscriptomicsChronic Psychological Stress regulates Visceral Adipocyte-mediated Glucose Metabolism and Inflammatory Circuits in male Rats
In this study we employed the chronic unpredictable stress (CUS) rat model that leads to anxiety features comparable to humans and validated in several published reports as a well-characterized model of depression symptoms with high predictive validity. Cytokines and activated intracellular kinase l...
ORGANISM(S): Rattus norvegicus 
2014-06-03 | E-GEOD-47754 | biostudies-arrayexpress
TranscriptomicsTranscription profiling by array of mouse amygdala to detect transcripts regulated by psychological stress
Detection of transcripts regulated by psychological stress in mouse amygdala. Prior to experiments mice were kept undisturbed for one week in their home cages. Restraint stress was performed during the light period of the circadian cycle. Control animals were left undisturbed and stressed animals w...
ORGANISM(S): Mus musculus 
2013-04-01 | E-MTAB-1519 | biostudies-arrayexpress
ProteomicsLiver mitochondria-associated ER membrane proteomics for studying the effects of ZiBuPiYin recipe on Zucker diabetic fatty rats after chronic psychological stress
Type 2 diabetes mellitus (T2DM) is a complex metabolic disease with multiple etiologies, involving both genetic and environmental factors. With changes associated with modern life, increasing attention has been paid to chronic psychological stressors such as work stress. Chronic psychological stress...
ORGANISM(S): Rattus norvegicus (Rat) 
2022-10-25 | PXD029226 | Pride
Type 2 diabetes mellitus Chronic psychological stress Zibupiyin recipe Proteomics Mitochondria-associated er membrane 
MetabolomicsA Cross-Platform Metabolomics Comparison Identifies Serum Metabolite Signatures of Liver Fibrosis Progression in Chronic Hepatitis C Patients
Metabolomics offers new insights into disease mechanisms that is enhanced when adopting orthogonal instrumental platforms to expand metabolome coverage, while also reducing false discoveries by independent replication. Herein, we report the first inter-method comparison when using multisegment injec...
2023-08-22 | MTBLS3111 | MetaboLights
TranscriptomicsGenomic Counter-Stress Changes Induced by Mind-Body Practice
Mind-body practices that elicit the relaxation response (RR) have been used worldwide for millennia to prevent and treat disease. The RR is believed to be the counterpart to stress response and is characterized by decreased oxygen consumption, increased exhaled nitric oxide, and reduced psychologica...
ORGANISM(S): Homo sapiens 
2008-10-21 | E-GEOD-10041 | biostudies-arrayexpress
TranscriptomicsTranscription profiling of human peripheral mononuclear blood cells taken from survivors of psychological trauma a few hours after the trauma and four months later
PTSD - Posttraumatic stress disorder. 33 samples taken from PMBCs of survivors of psychological trauma, in two time points: in ER, few hours after the truma, and four months later. Some of the patients devepled chronic PTSD (17 samples) and others recovered and set to be the Control group (16 sample...
ORGANISM(S): Homo sapiens 
2007-10-03 | E-GEOD-860 | biostudies-arrayexpress
GenomicsTranscriptomic Responses to chronic psychological stress: Insights from Mouse Liver, Brain, and Testis
Transcriptomic Responses to chronic psychological stress: Insights from Mouse Liver, Brain, and Testis
PRJNA1133771 | ENA
Transcriptomicsb-Catenin Mediates the Development of Behavioral Resilience [smallRNA-Seq]
Here we show that ?-catenin mediates pro-resilient and anxiolytic effects in mice in the nucleus accumbens (NAc), a key brain reward region, an effect that is mediated by ?-catenin signaling in D2-type medium spiny neurons (MSNs) specifically. Conversely, blocking ?-catenin function in NAc promotes...
ORGANISM(S): Mus musculus 
2014-11-13 | E-GEOD-61295 | biostudies-arrayexpress
Genomicsb-Catenin Mediates the Development of Behavioral Resilience [ChIP-Seq]
Here we show that ?-catenin mediates pro-resilient and anxiolytic effects in mice in the nucleus accumbens (NAc), a key brain reward region, an effect that is mediated by ?-catenin signaling in D2-type medium spiny neurons (MSNs) specifically. Conversely, blocking ?-catenin function in NAc promotes...
ORGANISM(S): Mus musculus 
2014-11-13 | E-GEOD-61294 | biostudies-arrayexpress
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