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TranscriptomicsAltered genes expression profile of Rep2 mutants in Fission Yeast upon HU treatment.
Expression profiles indicate that C-terminal of rep2 is essential for its transactivation activity. Keywords: rep2 mutants cells treated with 8 mM HU for different time points vs wildtype untreated cells We analyzed 40 arrays for rep2 mutants cells treated with 8 mM HU to wild type cells.
ORGANISM(S): Schizosaccharomyces pombe 
2010-05-16 | E-GEOD-10901 | biostudies-arrayexpress
TranscriptomicsSchizosaccharomyces pombe ployg mutant cells expression profile.
Expression profiles of polg mutant cells reveal that many genes encoding proteins involved in cell wall biogenesis and stress response are induced, suggesting that polg mutant cells attempt to maintain growth potential and undergo extensive oxidative metabolism. Conversely, many genes encoding prot...
ORGANISM(S): Schizosaccharomyces pombe 
2007-09-28 | E-GEOD-5941 | biostudies-arrayexpress
TranscriptomicsDeconvolution of ChIP-chip MBF occupancies reveals the temporal recruitment of Rep2 at the MBF-target genes
Deconvolution analysis using Rpb1 ChIP-chip results distinguishes the Cdc10 bindings at the Rpb1-poor loci (promoters) from those at the Rpb1-rich loci (intragenic sequences). Importantly, Res1 binding at the Rpb1-poor loci, but not at the Rpb1-rich loci, are dependent on the Cdc10 function, suggest...
ORGANISM(S): Schizosaccharomyces pombe 
2010-11-26 | E-GEOD-9912 | biostudies-arrayexpress
TranscriptomicsAtf1-mediated active gene response to H2O2 challenge.
Here we present the study on ChIP-chip mapping of the genomic binding sites for Sty1, Atf1, and the Atf1's binding partner Pcr1; the genome-wide transcriptional profiling of the atf1 and pcr1 strains in response to H2O2; and the phenotypic assessment of ~90 Atf1/Pcr1-bound or unbound genes for growt...
ORGANISM(S): Schizosaccharomyces pombe 
2010-07-19 | E-GEOD-13053 | biostudies-arrayexpress
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