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MetabolomicsAn obligate aerobe adapts to hypoxia by hybridising fermentation with carbon storage
In soil ecosystems, obligately aerobic bacteria survive oxygen deprivation (hypoxia) by entering non-replicative persistent states. Little is known about how these bacteria rewire their metabolism to stay viable during persistence. The model obligate aerobe Mycobacterium smegmatis maintains redox ho...
2026-04-22 | MTBLS11404 | MetaboLights
UnknownAutoantibodies against 3-hydroxy-3-methylglutaryl-coenzyme A reductase in patients with statin-associated autoimmune myopathy.
Not available
S-EPMC3335400 | biostudies-literature
TranscriptomicsMiR-29a maintains mouse hematopoietic stem cell self-renewal by regulating Dnmt3a
Gene expression profiling from fine purified hematopoietic stem and progenitor cells of WT or miR-29a deletion. This anlaysis identified the up- and down-regulated genes from miR-29a deletion, and suggest that cell cycle regulators are significantly changed. The results demonstrate that the HSC lac...
ORGANISM(S): Mus musculus 
2015-03-03 | E-GEOD-58237 | biostudies-arrayexpress
TranscriptomicsGene expression patterns in response to GATA2 (WT and mutants) in HL-60 cells
GATA2 mutants were discovered in families predisposed to MDS/AML and in sporadic cases of CML-blast crisis. Promyelocytic HL-60 cells were transduced with lentiviral vectors that express GATA2 WT or T354M, 355delT or L359V mutants upon addition of 4-hydroxy tamoxifen (4HT). Microarrays were performe...
ORGANISM(S): Homo sapiens 
2011-08-19 | E-GEOD-29276 | biostudies-arrayexpress
ProteomicsHuman oocyte proteome and secretome
The proteome and secretome of human oocytes was studied by shotgun LCMSMS, starting from pools of 100 cells. Exploiting SP3, a novel technology for proteomic sample preparation using magnetic beads, we scaled down proteome analysis to single cells. Despite the low protein content of only ~100ng per...
ORGANISM(S): Homo Sapiens (ncbitaxon:9606) 
2021-11-15 | MSV000088387 | MassIVE
UnknownDevelopment and validation of a pre-trained language model for neonatal morbidities: a retrospective, multicentre, prognostic study.
Not available
S-EPMC12748047 | biostudies-literature
UnknownDefine and visualize pathological architectures of human tissues from spatially resolved transcriptomics using deep learning.
Not available
S-EPMC9440291 | biostudies-literature
TranscriptomicsUse of clinical chromosomal microarray in Chinese patients with autism spectrum disorder - implications of a copy number variation involving dpp10 (CGX-12)
Background: Array-Comparative-Genomic-Hybridization (aCGH) is recommended as first-tier genetic test for children with autism spectrum disorder (ASD). However, result interpretation can be challenging as copy number variants (CNVs) in non-European ASD patients is not well studied. To address this li...
ORGANISM(S): Homo sapiens 
2017-04-07 | E-MTAB-5665 | biostudies-arrayexpress
TranscriptomicsUse of clinical chromosomal microarray in Chinese patients with autism spectrum disorder - implications of a copy number variation involving dpp10 (Perkin Elmer CGX)
Background Array-Comparative-Genomic-Hybridization (aCGH) is recommended as first-tier genetic test for children with autism spectrum disorder (ASD). However, result interpretation can be challenging as copy number variants (CNVs) in non-European ASD patients is not well studied. To address this lit...
ORGANISM(S): Homo sapiens 
2017-04-07 | E-MTAB-5672 | biostudies-arrayexpress
UnknownIndividual participant data systematic review and meta-analysis of randomised controlled trials assessing adult mindfulness-based programmes for mental health promotion in non-clinical settings.
Not available
S-EPMC7615230 | biostudies-literature
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