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TranscriptomicsExpression data from conditional Klf5 knockout Pten-null mouse prostates
KLF5 is a basic transcription factor that regulates multiple biological processes, but its function in tumorigenesis appears contradictory in the current literature, with some studies showing tumor suppressor activity and others showing tumor promoting activity. In this study, we examined the functi...
ORGANISM(S): Mus musculus 
2014-06-21 | E-GEOD-58719 | biostudies-arrayexpress
TranscriptomicsNext-generation sequencing facilitates quantitative analysis of AcKLF5 and unAcKLF5 transcriptomes in xenografts of DU-145 cell line
KLF5 possesses both tumor-suppressing and tumor-promoting activities, though the mechanism controlling these opposing functions is unknown. In cultured non-cancerous epithelial cells, KLF5 converts from pro-proliferative to anti-proliferative activity upon TGFβ-induced acetylation, which sequential...
ORGANISM(S): Homo sapiens 
2014-03-29 | E-GEOD-56343 | biostudies-arrayexpress
UnknownClinical Outcomes and Response to Vericiguat According to Index Heart Failure Event: Insights From the VICTORIA Trial.
Not available
S-EPMC7666431 | biostudies-literature
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