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ProteomicsLC-MS/MS analysis of the cation-independent mannose 6-phosphate receptor (CI-MPR) from bovine serum
The cation-independent mannose 6-phosphate receptor (CI-MPR) is clinically significant in the treatment of patients with lysosomal storage diseases because it functions in the biogenesis of lysosomes by transporting mannose 6-phosphate (M6P)-containing lysosomal enzymes to endosomal compartments. Th...
ORGANISM(S): Bos taurus (Bovine) 
2024-05-20 | PXD052183 | Pride
Bovine Ci-mpr Lc-ms/ms 
UnknownSequence-dependent cargo recognition by SNX-BARs mediates retromer-independent transport of CI-MPR.
Not available
S-EPMC5674890 | biostudies-literature
UnknownInvolvement of CASP9 (caspase 9) in IGF2R/CI-MPR endosomal transport.
Not available
S-EPMC8204962 | biostudies-literature
UnknownRare VPS35 A320V Variant in Taiwanese Parkinson's Disease Indicates Disrupted CI-MPR Sorting and Impaired Mitochondrial Morphology.
Not available
S-EPMC7692537 | biostudies-literature
UnknownAP-1γ2 is an adaptor protein 1 variant required for endosome-to-Golgi trafficking of the mannose-6-P receptor (CI-MPR) and ATP7B copper transporter
Not available
S-EPMC10909764 | biostudies-literature
TranscriptomicsAirn transcriptional overlap but not its lncRNA products induce imprinted Igf2r silencing.
To test if the imprinted long non-coding RNA (lncRNA) Airn transcription or its product silences the protein-coding Igf2r gene, we shortened the endogenous lncRNA to four different lengths by inserting polyadenylation (polyA) cassettes on the paternal chromosome via homologous recombination in ES ce...
ORGANISM(S): Mus musculus 
2012-12-20 | E-GEOD-41444 | biostudies-arrayexpress
ProteomicsComparative analyses of the N-glycoproteomes in HCT116 cancer cells and their non-tumorigenic DNMT1/3b double knockout (DKO1) cells and insight into the Mannose-6-phosphate pathway
N-glycoproteomic analyses provide valuable resources for investigation of cancer mechanisms, biomarkers, and therapeutic targets. Here, we mapped and compared the site-specific N-glycoproteomes of colon cancer HCT116 cells and isogenic non-tumorigenic DNMT1/3b double knockout (DKO1) cells using Fbs...
ORGANISM(S): Homo sapiens (Human) 
2023-01-17 | PXD035301 | Pride
Mannose-6-phosphate (m6p) Fbs1-gyr N-glycoproteome N-glycosylation Paucimannose 
UnknownThe glycan-binding properties of the cation-independent mannose 6-phosphate receptor are evolutionary conserved in vertebrates.
Not available
S-EPMC3355666 | biostudies-literature
UnknownTGN exit of the cation-independent mannose 6-phosphate receptor does not require acid hydrolase binding.
Not available
S-EPMC4292573 | biostudies-literature
UnknownAssociation of mean platelet volume-to-platelet count ratio for 24-hour mortality in patients with severe trauma.
Not available
S-EPMC12401459 | biostudies-literature
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