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TranscriptomicsIncreased resistance to proteasome inhibitors in multiple myeloma mediated by cIAP2 overexpression - implications for a combinatorial treatment
In this study we wanted to investigate the role of cIAP2 in drug resistance, the plausible mechanisms underlying this resistance and possible strategies to overcome this by combinatorial treatment in human MM cell lines containing a TRAF3 mutation Gene expression profiling of the human MM cell line ...
ORGANISM(S): Homo sapiens 
2015-05-18 | E-GEOD-63520 | biostudies-arrayexpress
GenomicsBIRC3 (encoding cIAP2) variants are associated with Crohn’s Disease.
BIRC3 (encoding cIAP2) variants are associated with Crohn’s Disease.
PRJNA1274021 | ENA
UnknownCrystal structures of the TRAF2: cIAP2 and the TRAF1: TRAF2: cIAP2 complexes: affinity, specificity, and regulation.
Not available
S-EPMC2855162 | biostudies-literature
UnknownTargeting Upregulated cIAP2 in SOX10-Deficient Drug Tolerant Melanoma.
Not available
S-EPMC10527992 | biostudies-literature
UnknownCellular inhibitor of apoptosis 2 (cIAP2) restricts neuroinflammation during experimental autoimmune encephalomyelitis.
Not available
S-EPMC9208101 | biostudies-literature
UnknowncIAP2 represses IKKα/β-mediated activation of MDM2 to prevent p53 degradation.
Not available
S-EPMC3507496 | biostudies-literature
UnknownUSP11-dependent selective cIAP2 deubiquitylation and stabilization determine sensitivity to Smac mimetics.
Not available
S-EPMC4532773 | biostudies-literature
UnknownHepatitis B virus induces sorafenib resistance in liver cancer via upregulation of cIAP2 expression.
Not available
S-EPMC7988944 | biostudies-literature
GenomicsTargeting cIAP2 in a novel senolytic strategy prevents glioblastoma recurrence after radiotherapy
Targeting cIAP2 in a novel senolytic strategy prevents glioblastoma recurrence after radiotherapy
PRJNA1134141 | ENA
UnknownTranslation of cIAP2 mRNA is mediated exclusively by a stress-modulated ribosome shunt.
Not available
S-EPMC2268400 | biostudies-literature
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