Sort   by:  
 Page size 
TranscriptomicsRNA-Seq of rRNA depleted circulating endothelial progenitor cells (cEPCs) in trisomy 21 and euploid samples
Massive-scale RNA-seq on rRNA-depleted samples allowed us to survey in a specific cell type, affected in Down syndrome, the complete set of coding and non-coding RNA species - emerging as novel contributors to pathogenic mechanisms - to an unprecedented level of resolution and sensitivity. In partic...
ORGANISM(S): Homo sapiens 
2011-05-04 | E-GEOD-27443 | biostudies-arrayexpress
TranscriptomicsRNA-Sequencing of human papillary thyroid carcinomas
RNA-Sequencing analysis of 18 papillary thyroid carcinoma biopsies and of 4 healthy donors' thyroids. In this analysis we assessed differential gene expression and investigated the mutational landscape in this tumor type. Analysis of gene fusion was also performed, leading to the identification of a...
ORGANISM(S): Homo sapiens 
2015-05-01 | E-GEOD-64912 | biostudies-arrayexpress
TranscriptomicsDown syndrome
Endothelial progenitor cells were isolated from euploid and Down syndrome (DS) affected individuals. Gene expression was analyzed on total RNA extracted before or after infection with a human pathogen Bartonella hensaele. For euploid uninfected and infected cells, 2 biological replicates were perfor...
ORGANISM(S): Homo sapiens 
2010-01-12 | E-MTAB-312 | biostudies-arrayexpress
TranscriptomicsRNA-Sequencing shows novel transcriptomic signatures in failing and non-failing human heart
The knowledge of an expression network signature in end-stage heart failure (HF) diseased hearts may offer important insights into the complex pathogenesis of advanced cardiac failure, as well as it may provide potential targets for therapeutic intervention. In this study, the NGS sequencing of RNA ...
ORGANISM(S): Homo sapiens 
2015-11-01 | E-GEOD-71613 | biostudies-arrayexpress
Sort   by:  
 Page size