Circulating biomarkers

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Unknown (6931)
Genomics (933)
Transcriptomics (418)
Proteomics (211)
Methylation profiling (28)
Other (22)
Metabolomics (21)
Clinical (18)
Models (2)
Genomic (2)

Organisms

Homo sapiens (680)
Mus musculus (90)
Rattus norvegicus (43)
synthetic construct (21)
Bos taurus (17)
Macaca mulatta (6)
Equus caballus (4)
Canis lupus familiaris (4)
Sus scrofa (4)
Macaca fascicularis (3)
Ovis aries (3)
Human immunodeficiency virus 1 (3)
Danio rerio (2)
Betapolyomavirus macacae (2)
JC polyomavirus (2)
Merkel cell polyomavirus (2)
Betapolyomavirus hominis (2)
Human alphaherpesvirus 2 (2)
Human alphaherpesvirus 1 (2)
Papio anubis (2)
Micropterus salmoides (1)
Felis catus (1)
Campylobacter jejuni (1)
Mus musculus cytomegalovirus 2 (1)
Cervus canadensis (1)
Cytomegalovirus (1)
Solea senegalensis (1)
Lymphocryptovirus (1)
Rhadinovirus (1)
Trachemys scripta (1)

Organisms

Homo sapiens (427)
Mus musculus (51)
Rattus norvegicus (16)
Bos taurus (8)
Macaca mulatta (3)
Ovis aries (3)
Canis lupus familiaris (3)
Sus scrofa (3)
Macaca fascicularis (2)
Papio anubis (2)
Trachemys scripta (1)
Solea senegalensis (1)
Mammalia (1)
Oncorhynchus mykiss (1)
synthetic construct (1)

Repository

ENA (637)
geo (494)
biostudies-arrayexpress (261)
pride (105)
EGA (56)
iProX (24)
MassIVE (20)
MetaboLights (20)
PanoramaPublic (10)
BioModels (2)
dbGaP (2)
jPOST (2)
PAXDB (2)
GNPS (1)
GPMDB (1)

Tissue

Blood plasma (43)
Blood serum (24)
Blood cell (10)
Blood (8)
Cell culture (5)
B cell (3)
Brain (3)
Heart (3)
Liver (3)
Cerebrospinal fluid (2)
Epithelial cell (2)
Extracellular vesicle (2)
Lung (2)
Lymph node (2)
Macrophage (2)
Skeletal muscle (2)
T cell (2)
Bile (1)
Blood platelet (1)
Bone marrow (1)
Breast (1)
Colon epithelial cell (1)
Dendritic cell (1)
Endocrine pancreas (1)
Endothelial cell of coronary artery (1)
Endothelial cell of umbilical vein (1)
Erythroblast (1)
Glioblastoma cell (1)
Hemolymph (1)
IgG short lived plasma cell (1)

Disease

Colorectal Neoplasms (9)
Breast cancer (8)
Cardiovascular system disease (8)
Aortic valve stenosis (3)
Disease free (3)
Human immunodeficiency virus infectious disease (3)
Intracerebral hemorrhage (3)
Malignant neoplasm of ovary (3)
Normal (2)
Neoplastic Cells, Circulating (2)
Colorectal cancer (2)
COVID-19 (2)
Colon cancer (2)
Glioblastoma (2)
Lung cancer (2)
Melanoma (2)
Vitamin B12 deficiency (1)
Post-stasis (1)
Renal cancer (1)
Rheumatoid arthritis (1)
Locally advanced rectal cancer (1)
Head and neck squamous cell carcinoma (1)
MGUS (1)
Non-small cell lung carcinoma (1)
Gastrointestinal cancer (esophageal cancer, stomach cancer, colorectal cancer) (1)
Meningioma (1)
Carcinoma, Renal Cell (1)
Neoplasm Metastasis (1)
Rectal Neoplasms (1)
Not Available (1)

Technology Type

Mass Spectrometry (105)
Shotgun proteomics (51)
Bottom-up proteomics (23)
SWATH MS (16)
Data-independent acquisition (15)
Mass spectrometry (12)
Data-dependent acquisition (11)
NMR spectroscopy (4)
Affinity purification coupled with mass spectrometry proteomics (4)
Gel-based experiment (4)
Mass spectrometry assay (3)
Top-down proteomics (3)
Illumina HiSeq 2000 (2)
NMR spectroscopy assay (2)
All-ion fragmentation (2)
DiaPASEF (2)
SRM/MRM (2)
ILLUMINA, Illumina HiSeq 4000, Illumina MiSeq (1)
Illumina HiSeq 2500, ILLUMINA (1)
Illumina HiSeq 2000, Illumina MiSeq (1)
Illumina (1)
Affinity proteomics (1)
Olink affinity proteomics (1)
SomaScan affinity proteomics (1)

Instrument Platform

Q Exactive (6)
Orbitrap Exploris 480 (4)
Affymetrix GeneChip(R) HT Scanner (3)
Agilent 2100 Bioanalyzer (2)
Illumina NovaSeq X (2)
NextSeq 550 (2)
Illumina HiSeq 2500 (2)
Illumina NovaSeq 6000 (2)
Illumina HiSeq 2000 (2)
Illumina HiSeq 3000 (2)
Orbitrap Eclipse (2)
Q Exactive Plus (2)
Illumina HiSeq 2000 platform (1)
G2565BA DNA microarray scanner (1)
Agilent microarray Scanner (1)
Agilent Microarray Hybridization Chamber Kit and Hybridization oven rotator (1)
Agilent miRNA Complete Labeling and Hyb Kit (1)
Extraction kit (1)
Genetix aQuire (1)
GeneChip2 Scanner 3000 7G (1)
GeneChip2 Hybridization Oven 640 (1)
Illumina Genome Analyzer II (1)
Ion Torrent PGM (1)
None (1)
NextSeq 500 (1)
Instrument (1)
6495C Triple Quadrupole LC/MS (1)
Agilent 6495C Triple Quadrupole (1)
Orbitrap Astral (1)
Orbitrap Fusion (1)

Publication Date

2025 (102)
2026 (97)
2022 (67)
2014 (66)
2023 (64)
2013 (63)
2024 (63)
2021 (62)
2015 (53)
2019 (47)
2020 (45)
2011 (41)
2018 (36)
2016 (32)
2012 (32)
2017 (27)
2010 (21)
2008 (8)
2009 (7)
2007 (3)
2006 (3)

UNIPROT ID/AC

5833.MAL13P1.267 (2)
5833.MAL13P1.269 (2)
5833.MAL13P1.325 (2)
5833.MAL13P1.334 (2)
5833.MAL7P1.78 (2)
5833.MAL8P1.208 (2)
5833.MAL8P1.320 (2)
5833.PF11_0033 (2)
5833.PF11_0263 (2)
5833.PF11_0512 (2)
5833.PF13_0305 (2)
5833.PF13_0321 (2)
5833.PF14_0001 (2)
5833.PF14_0009 (2)
5833.PF14_0173 (2)
5833.PF14_0734 (2)
5833.PF14_0751 (2)
5833.PF14_0756 (2)
5833.PF14_0759 (2)
5833.PFA0105w (2)
5833.PFA0120c (2)
5833.PFA0705c (2)
5833.PFB0050c (2)
5833.PFB0280w (2)
5833.PFB0925w (2)
5833.PFB0946c (2)
5833.PFC1011c (2)
5833.PFC1075w (2)
5833.PFD0075w (2)
P42212 (1)

CHEBI ID

CHEBI:64566 (6)
CHEBI:16737 (6)
CHEBI:16919 (6)
CHEBI:28842 (5)
CHEBI:17203 (5)
CHEBI:73054 (5)
CHEBI:15756 (5)
CHEBI:72535 (4)
CHEBI:91312 (4)
CHEBI:67057 (4)
CHEBI:85762 (4)
CHEBI:74349 (4)
CHEBI:74968 (4)
CHEBI:90452 (4)
CHEBI:42504 (4)
CHEBI:72998 (4)
CHEBI:32365 (4)
CHEBI:30805 (4)
CHEBI:83358 (4)
CHEBI:64481 (4)
CHEBI:16755 (4)
CHEBI:73858 (4)
CHEBI:28875 (4)
CHEBI:15428 (4)
CHEBI:116314 (4)
CHEBI:73067 (4)
CHEBI:18183 (4)
CHEBI:18050 (4)
CHEBI:36005 (4)
CHEBI:16347 (4)

Metabolite Name

Creatinine (6)
Glucose (5)
Creatine (5)
Choline (4)
Stearic acid (4)
Alanine (4)
Chenodeoxycholic acid (3)
Hyodeoxycholic acid (3)
Pentadecanoic acid (3)
Glycine (3)
Glycerol (3)
Betaine (3)
L-Proline (3)
Ornithine (3)
Deoxycholic acid (3)
Glycocholic acid (3)
Arachidonic acid (3)
Proline (3)
Isoleucine (3)
Dodecanoic acid (3)
Dodecanedioic acid (3)
Myristic acid (3)
L-Carnitine (3)
Caffeine (3)
Hippuric acid (3)
L-Phenylalanine (3)
PC(18:0/22:4) (2)
PC(14:0/20:4) (2)
PC(18:0/20:2) (2)
PC(18:1/20:4) (2)

First Public Date

2025 (86)
2024 (77)
2026 (71)
2023 (57)
2022 (55)
2019 (51)
2014 (50)
2021 (49)
2020 (44)
2017 (28)
2015 (24)
2018 (21)
2016 (12)
2013 (12)

Modelling Approach

Ordinary differential equation model (2)

Study status

Recruiting (8)
Not provided (4)
Completed (3)
Not yet recruiting (2)
Terminated (1)

Lab affiliation

Instituto de Investigaciones Sanitarias de Santiago de Compostela (6)
Research Officer|Proteomics and Small Molecule Mass Spectrometry Laboratory | Central Analytical Research Facility (CARF)| Queensland University of Technology | Address: Level 6, P Block, Gardens Point Campus, 2 George St Brisbane QLD 4000 (2)
Vanderbilt University (2)
1 Department of Anaesthesiology, LMU University Hospital, Ludwig-Maximilian-University (LMU), Munich, Germany 2 Walter Brendel Center of Experimental Medicine, Research Unit Immune Function and Immune Metabolism, Ludwig-Maximilian-University (LMU), Munich, Germany (1)
1. INSERM U1287, Université Paris-Saclay, Gustave Roussy Cancer Center, Villejuif, France 2. Université Paris-Saclay, Faculté de Médecine, Le Kremlin-Bicêtre, France (1)
1. Research Institute for Medical and Health Sciences, University of Sharjah, Sharjah 27272, United Arab Emirates. 2. College of Pharmacy, Department of Medicinal Chemistry, University of Sharjah, 27272, United Arab Emirates (1)
1Singapore Institute for Clinical Sciences, Agency for Science, Technology and Research (A*STAR), Singapore 2 Lee Kong Chian School of Medicine, Nanyang Technological University (NTU), Singapore 3 Cardiovascular and Metabolic Disorders Program, Duke-NUS Medical School, Singapore 4Yong Loo Lin School of Medicine, National University of Singapore (NUS), Singapore 5 Department of Endocrinology, Tan Tock Seng Hospital (TTSH), Singapore (1)
Aging Institute, University of Pittsburgh School of Medicine/UPMC (1)
Assistant Professor, Departments of Oncology & Pathology, McGill University Principal Investigator, Cancer Research Program, MUHC-RI 1001 Decarie Blvd, EM2.2218 514.934.1934 ext 76307 Montréal, Canada (1)
Assistant Professor, Pharmacology Dept, UNC-Chapel Hill (1)
Biological Mass Spectrometry Lab, Department of Translational Medicine (DiMeT), Center for Translational Research on Autoimmune & Allergic Diseases - CAAD, University of Piemonte Orientale - UPO (1)
Biological Mass Spectrometry Lab, Department of Translational Medicine, University of Piemonte Orientale (1)
Biomedical Research in Cancer Stem Cells Group. Pathology Department. Vall d'Hebron Research Institute (VHIR). Barcelona, Spain (1)
Boston University School of Medicine (1)
Brigham and Women's Hospital, Harvard Medical School (1)
Center for Advanced Studies and Technology, "G. d'Annunzio" University, Chieti, Italy (1)
Center for Neuroscience and Cell Biology of the University of Coimbra, Portugal (1)
Center for Technological Development in Health, Oswaldo Cruz Foundation, Rio de Janeiro, Brazil (1)
Centre for Neuroscience and Trauma, Blizard Institute, Queen Mary University of London, 4 Newark Street, London, E1 2AT, UK. (1)
Clinical Laboratory of Honghui Hospital, Xi'an Jiaotong University (1)
Columbia University Irving Medical Center (1)
DEPARTMENT OF TROPICAL MEDICINE,SCHOOL OF TROPICAL MEDICINE, KOLKATA, WEST BENGAL, INDIA (1)
Department for BioMedical Research (DBMR), University of Bern, 3008 Bern, Switzerland (1)
Department of Biochemistry and Tissue Biology, Institute of Biology, University of Campinas (UNICAMP), Campinas, Brazil (1)
Department of Biology, Institute of Molecular Systems Biology, ETH Zurich, Zurich, CH-8093, Switzerland ( lab head ) (1)
Department of Biomedical Sciences, Panum Institute, University of Copenhagen, Denmark (1)
Department of Cardiovascular Surgery, University Heart & Vascular Center Hamburg, Germany (1)
Department of Immunotechnology, Lund University, Lund, Sweden (1)
Department of Microbiology and Immunology, University of Melbourne at the Peter Doherty Institute for Infection and Immunity, Melbourne 3000, Australia (1)
Department of Microbiology, Immunology and Pathology; Colorado State University, Fort Collins, CO (1)

Keyword

Bevacizumab (2)
Colorectal cancer, cetuximab, biomarker, prometheus (1)
Biomaker (1)
Aspirina (1)
METFORAL 850 mg compresse rivestite con film (1)
Circulating cell free DNA (1)
Predictive marker (1)
Prognostic marker (1)
Treatment efficiency (1)
High Risk (1)
Molecular Profiling (1)
Hematological (1)
Early diagnosis (1)
NGS (1)
Next Generation Sequencing (1)
Tumor heterogeneity (1)
Tumor evolution (1)
Blood (1)
Metformin (1)
Liquid Biopsy (1)
Circulating tumor cells (1)
Circulating Tumor Cells (1)
Circulating Tumor DNA (1)
Circulating tumor DNA (1)
Sorafenib (1)
Targeted therapy (1)
CtDNA (1)
Metastatic (1)
Rectal cancer (1)
Aspirin (1)

IsPrivate

False (2)

Modification

Not available (1)

Study type

Transcription profiling by array (143)
Proteomic profiling by array (38)
Methylation profiling by array (13)
RNA-seq of coding RNA (13)
Other (10)
Observational (10)
RNA-seq of non coding RNA (9)
Transcription profiling by RT-PCR (8)
MicroRNA profiling by array (6)
Interventional (6)
Comparative genomic hybridization by array (4)
Human - One-color microarray (2)
ChIP-chip by array (2)
ChIP-seq (2)
RNA-seq of coding RNA from single cells (2)
Observational patient registry (2)
Unknown experiment type (1)
MeDIP-seq (1)
Genotyping by array (1)
MBD-seq (1)
MicroRNA profiling by high throughput sequencing (1)
Bisulfite-seq (1)
DNA-seq (1)
Methylation profiling by high throughput sequencing (1)
RNA-seq of total RNA (1)

Release Date

2022 (948)
2021 (830)
2023 (813)
2025 (783)
2020 (673)
2024 (632)
2019 (477)
2018 (421)
2017 (346)
2016 (293)
2015 (238)
2014 (194)
2013 (138)
2026 (126)
2011 (87)
2012 (86)
2010 (42)
2009 (35)
2008 (13)
2006 (9)
2007 (6)
2004 (2)

Location

France (4)
Sweden (2)
Austria (2)
Finland (1)
Norway (1)
Slovenia (1)
Saudi Arabia (1)
Taiwan (1)
China (1)
South Korea (1)
Italy (1)
Canada (1)
Australia (1)
Japan (1)

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Circulating cell populations as response predictors and targets to improve immunotherapy in metastatic lung cancer

The effectiveness of immunotherapy varies among patients with advanced non-small cell lung cancer (NSCLC). Here we investigated the baseline immune status in stage IV NSCLC patients treated with anti-PD-1 plus chemotherapy to understand the immune mechanisms and unveil systemic markers associated...

2025-10-16 | MTBLS13150 | MetaboLights

Untargeted 1 H NMR-based metabolomics unveils distinct circulating biochemical signatures between treatment-resistant and non-treatment-resistant Schizophrenia patients: a pilot study

Schizophrenia is a severe psychiatric disorder impacting roughly 1% of individuals. The effectiveness of antipsychotic therapy greatly varies, with around 30% of patients categorised as treatment-resistant (TRS). TRS is characterised by a lack of response to at least two clinical trials invo...

2025-10-01 | MTBLS12709 | MetaboLights

Hyocholic acid species as novel biomarkers for metabolic disorders

Hyocholic acid (HCA) is a major bile acid (BA) species in the BA pool of pigs, a species known for its exceptional resistance to spontaneous development of diabetic phenotypes. HCA and its derivatives are also present in human blood and urine. We investigate whether human HCA profiles can predict th...

2021-10-06 | MTBLS2343 | MetaboLights

A Divergent Selection on Breast Meat Ultimate pH, a Key Factor for Chicken Meat Quality, is Associated With Different Circulating Lipid Profiles

BACKGROUND: Chicken meat has become a major source of protein for human consumption. However, the quality of the meat is not yet under control, especially since pH values that are too low or too high are often observed. In an attempt to get a better understanding of the genetic a...

2022-06-01 | MTBLS2970 | MetaboLights

Analysis of the impact of cellular miRNA signatures on the profiles of circulating miRNA biomarkers (variability data)

Circulating miRNAs are an emerging class of biomarkers correlating their specific expression patterns to disease states. A considerable proportion of hematopoietically-derived miRNAs are present in plasma with the ability to confound the signature of true circulating miRNA species. We use microarray...

ORGANISM(S): Homo sapiens

2011-06-17 | E-GEOD-27253 | biostudies-arrayexpress

Circulating microRNA profiles during the bovine oestrous cycle

Up to 50% of ovulations go undetected in modern dairy herds due to attenuated oestrus behavior and a lack of high-accuracy methods for detection of fertile oestrus. This significantly reduces overall herd productivity and constitutes a high economic burden to the dairy industry. MicroRNAs (miRNAs) a...

ORGANISM(S): Bos taurus

2016-07-29 | E-GEOD-81050 | biostudies-arrayexpress

Analysis of the impact of cellular miRNA signatures on the profiles of circulating miRNA biomarkers (fractionation data)

ORGANISM(S): Homo sapiens

2011-06-17 | E-GEOD-27230 | biostudies-arrayexpress

Impact of cellular miRNAs on the biomarker signatures of circulating miRNAs

This SuperSeries is composed of the following subset Series: GSE27230: Analysis of the impact of cellular miRNA signatures on the profiles of circulating miRNA biomarkers (fractionation data) GSE27253: Analysis of the impact of cellular miRNA signatures on the profiles of circulating miRNA biomarker...

ORGANISM(S): Homo sapiens

2011-06-17 | E-GEOD-27256 | biostudies-arrayexpress

Circulating MicroRNAs as Biomarkers of Metabolic Syndrome

PRJNA648409 | ENA

Single-Cell Identification of Melanoma Biomarkers in Circulating Tumor Cells

PRJNA1074402 | ENA

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8586 Results

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