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Estrogen Receptor subtypes (ERα and ERβ) are transcription factors sharing similar structure, however, they often perform opposite roles in breast cancer’s cell proliferation and tumor progression. Besides the well-characterized genomic actions of ERs upon ligand binding, rapid non-genomic cytoplasm...
ORGANISM(S): Homo sapiens (Human) 
2015-03-11 | PXD001202 | Pride
Tissue-scale architecture and mechanical properties instruct cell behavior in physiological and diseased conditions, but our understanding of the underlying mechanisms remains fragmentary. Here we show that ECM stiffness, spatial confinements, and applied forces including stretching of the mouse ski...
ORGANISM(S): Homo sapiens (Human) 
2024-09-02 | PXD040502 | Pride
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