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Transcriptional profiling of peripheral blood CD56+ natural killer cells from active JSLE patients, patients with low disease activity and healthy controls.
ORGANISM(S): Homo sapiens 
T-cells are important in the pathogenesis of juvenile-onset systemic lupus erythematosus (JSLE). Transcriptomic analysis of FACS sorted primary CD4+ and CD8+ T-cells was performed to assess differential gene expression in patient groups.
ORGANISM(S): Homo sapiens 
Sexual dimorphisms, which vary depending on age group and pubertal status, have been described across both the innate and adaptive immune system. We explored the influence of sex hormones on Treg differential gene expression in the context of adolescent health (cisgender and transgender individuals)...
ORGANISM(S): Homo sapiens 
Transcriptional profiling of peripheral blood CD8+ T cells from juvenile systemic lupus erythematosus (JSLE) patients and healthy controls.
ORGANISM(S): Homo sapiens 
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