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GenomicsKUL-MEL Laboratory of Molecular Endocrinology, KU Leuven
Data Access Committee EGAC00001000260
EGAC00001000260 | EGA
GenomicsAndrogen receptor uses relaxed response element stringency for selective chromatin binding and transcriptional regulation in vivo
We report the in vivo androgen receptor (AR) binding sites in caput epididymis of intact SPARKI and wild-type mice using ChIP-sequencing. SPARKI (specificity affecting androgen receptor knock-in) mouse line has the second zinc finger of AR replaced by that of glucocorticoid receptors. In vivo analys...
ORGANISM(S): Mus musculus 
2014-01-21 | E-GEOD-51106 | biostudies-arrayexpress
TranscriptomicsGlucocorticoid and androgen receptor profiling (ChIP-seq) in U2OS-GR and U2OS-AR cells upon hormone treatment
We performed ChIP-seq targeting the glucocorticoid receptor (GR) in the U2OS-GR cell line and the androgen receptor (AR) in the U2OS-AR cell line. The cell lines are derived from U2OS ATTC:HTB-96 and stably transfected with an expression construct for either rat GR or human AR, respectively. The U2O...
ORGANISM(S): Homo sapiens 
2021-03-09 | E-MTAB-9616 | biostudies-arrayexpress
Genomicsena-DATASET-KU-MEL-12-04-2016-11:46:48:538-274 - samples
Exome sequencing of high-risk prostate cancer
EGAD00001002009 | EGA
Genomicsena-DATASET-KU-MEL-12-04-2016-11:49:00:586-275 - samples
high-throughput sequencing of methylated and hydroxymethylated DNA from tumor and non-tumor tissue of patients with high-risk prostate cancer
EGAD00001002010 | EGA
GenomicsExomes of High-risk Prostate cancer
DNA extracted from tumoral tissue of 39 patients was used for exome sequencing. As a comparison, DNA extracted from blood was used as a non-tumoral control. DNA was captured using the EZ SeqCap v3 exome kit from Roche and sequenced using an Illumina HiSeq instrument.
EGAS00001001015 | EGA
Genomics(h)MeDIP-Seq of high-risk prostate cancer
Immunoprecipitation of methylated and hydroxymethylated DNA was performed on DNA isolated from tumoral and non-tumoral prostate tissue of patients with high-risk disease. Samples were sequenced on the Illumina HiSeq as 50 bp single end.
EGAS00001001019 | EGA
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