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UnknownStructures of open (R) and close (T) states of prephenate dehydratase (PDT)--implication of allosteric regulation by L-phenylalanine.
Not available
S-EPMC3366492 | biostudies-literature
UnknownProviding Scale to a Known Taxonomic Unknown-At Least a 70-Fold Increase in Species Diversity in a Cosmopolitan Nominal Taxon of Lichen-Forming Fungi.
Not available
S-EPMC9146994 | biostudies-literature
UnknownMolecular determinants of pro-arrhythmia proclivity of d- and l-sotalol via a multi-scale modeling pipeline.
Not available
S-EPMC8906354 | biostudies-literature
UnknownPhase I study of temsirolimus in pediatric patients with recurrent/refractory solid tumors.
Not available
S-EPMC3138720 | biostudies-literature
TranscriptomicsExposure of cystic fibrosis bronchial epithelial cells (CFBE 41 o-) to Pseudomonas aeruginosa (PA01) biofilms
In the clinical setting, mutations in the CFTR gene enhance the inflammatory response to P. aeruginosa (PA01) infection, but measurements of the inflammatory response to pathogen stimulation by isolated airway epithelia can yield variable results. In this series, we exposed CFBE41o- cells over-expre...
ORGANISM(S): Homo sapiens 
2011-07-31 | E-GEOD-30439 | biostudies-arrayexpress
TranscriptomicsThe effect of homocysteine on human aortic smooth muscle cells
Vascular calcification is a common manifestation of atherosclerosis and involves cell-mediated processes similar to the formation of bone (osteogenesis). Elevated plasma levels of homocysteine are an independent risk factor for atherosclerotic vascular disease but the underlying mechanisms remain un...
ORGANISM(S): Homo sapiens 
2008-10-21 | E-GEOD-9490 | biostudies-arrayexpress
Transcriptomicschico mutant
Comparison of wild type and heterozygote and homozygote chico mutants ( Clancy, et al. Extension of Life-Span by Loss of CHICO, a Drosophila Insulin Receptor Substrate Protein. Science 292 (5514), 104.) on Affymetrix Drosophila2 GeneChip. The flies (Drosophila melanogaster) are 7 day old adult fema...
ORGANISM(S): Drosophila melanogaster 
2007-06-06 | E-MEXP-1099 | biostudies-arrayexpress
TranscriptomicsMembranous Expression of Ectodomain Isoforms of the Epidermal Growth Factor Receptor (EGFR) Predicts Outcome after Chemoradiotherapy of Lymph Node Negative Cervical Cancer
We compared the prognostic significance of ectodomain isoforms of the epidermal growth factor receptor (EGFR), which lack the tyrosine kinase (TK) domain, with that of the full length receptor and its autophosphorylation status in cervical cancers treated with conventional chemoradiotherapy. We furt...
ORGANISM(S): Homo sapiens 
2011-07-18 | E-GEOD-29817 | biostudies-arrayexpress
ModelsClancy2001_Kchannel
This model is according to the paper Cellular consequences of HEGR mutations in the long QT syndrome: precursors to sudden cardiac death. The author used Markovian model of cardiac Ikr in the paper. Figure4B in the paper has been reproduced using CellDesigner3.5.1. The cell is depola...
2024-09-02 | BIOMD0000000121 | BioModels
ModelsClancy2002_CardiacSodiumChannel_WT
The model is according to the paper Na+ Channel Mutation That Causes Both Brugada and Long-QT Syndrome Phenotypes: A Simulation Study of Mechanism Original model comes from ModelDB with accession number: 62661. This is the wide type model. All the values and reactions obtained from D...
2024-09-02 | BIOMD0000000126 | BioModels
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