Sort   by:  
 Page size 
TranscriptomicsExpression data from the seed coats of black (iRT) and brown (irT) soybean variant for alleles of the R locus
The seed coat of black (iRT) soybean with the dominant R allele begins to accumulate cyanic pigments at the transition stage of seed development (300 – 400 mg fresh seed weight), whereas the brown (irT) nearly-isogenic seed coat with the recessive r allele lacks cyanic pigments at all stages of seed...
ORGANISM(S): Glycine max 
2011-08-22 | E-GEOD-26208 | biostudies-arrayexpress
MetabolomicsMultiomic profiling of iron-deficient infant monkeys reveals alterations in neurologically important biochemicals in serum and cerebrospinal fluid before the onset of anemia

The effects of iron deficiency (ID) during infancy extend beyond the hematologic compartment and include short- and long-term adverse effects on many tissues including the brain. However, sensitive biomarkers of iron-dependent brain health are lacking in humans. To determine whether serum and cer...

2022-07-12 | MTBLS3388 | MetaboLights
TranscriptomicsRNA seq of pancreatic islets isolated from free fatty acid receptor 3 knockout (Ffar3 KO) and wildtype (Ffar3 WT) male mice
The short chain fatty acid (SCFA) receptor (free fatty acid receptor-3; FFAR3) is expressed in pancreatic beta cells; however, its role in insulin secretion is not clearly defined. Here, we examined the role of FFAR3 in insulin secretion. Using islets from global knockout FFAR3 (Ffar3-/-) mice, we e...
ORGANISM(S): Mus musculus 
2016-07-03 | E-GEOD-67991 | biostudies-arrayexpress
TranscriptomicsYap and Taz regulate retinal pigment epithelial cell fate
The optic vesicle comprises a pool of bi-potential progenitor cells from which the retinal pigment epithelium (RPE) and neural retina fates segregate during ocular morphogenesis. Several transcription factors and signaling pathways have been shown to be important for RPE maintenance and different...
ORGANISM(S): Danio rerio 
2015-08-06 | E-GEOD-71681 | biostudies-arrayexpress
TranscriptomicsTranscriptome of phosphomimetic and phosphoablative kasB mutants of Mycobacterium tuberculosis
Mechanisms governing Mycobacterium tuberculosis acid-fastness and its capacity to induce long-term infections remain unknown. Serine/Threonine phosphorylation represents an emerging theme allowing mycobacteria to adapt their cell envelope structure/composition in response to environmental changes. W...
ORGANISM(S): Mycobacterium tuberculosis 
2014-04-01 | E-GEOD-47640 | biostudies-arrayexpress
TranscriptomicsTranscriptome analyses of skeletal muscle in αB-crystallin/HspB2 knockout and wild-type mice on a normal or high fat diet
We profiled the skeletal muscle transcriptome between wild type and αB-crystallin/HspB2 knock mice exposed to normal chow and high fat diets to examine the role of αB-crystallin/HspB2 in diet induced obesity. Combined with metabolic profiling of the mice, these data reveal that αB-crystallin/HspB2...
ORGANISM(S): Mus musculus 
2015-09-01 | E-GEOD-66557 | biostudies-arrayexpress
ProteomicsCasz1 interactome via BioID on primary mouse retinal cells
Control versus Casz1 BioID on mouse primary retinal cells. BioID constructs were introduced via nucleofection. Cultured cells were harvested, nuclei extracted, and BioID was performed as per standard procedures.
ORGANISM(S): Mus Musculus (ncbitaxon:10090) 
2020-06-17 | MSV000085598 | MassIVE
UnknownImproving health outcomes of people with diabetes: target setting for the WHO Global Diabetes Compact.
Not available
S-EPMC10420388 | biostudies-literature
TranscriptomicsAntibody detection of translocations (ADOT) in Ewing Sarcoma
We developed a new approach called antibody detection of translocations (ADOT) which combines a transcriptional microarray-based approach with a novel antibody-based detection method to detect translocations in cancer. ADOT allows for the accurate and sensitive identification of translocations and p...
ORGANISM(S): Homo sapiens 
2012-01-31 | E-GEOD-35450 | biostudies-arrayexpress
ProteomicsLKB1 regulates JNK-dependent stress signaling and apoptotic dependency of KRAS-mutant lung cancers
KRAS-mutant lung cancers frequently have inactivating mutations in LKB1, which enhances tumor growth, metastasis, and immune evasion. This study shows that LKB1 suppresses JNK stress signaling, and its loss in KRAS-mutant cells leads to JNK hyperactivation and apoptotic rewiring, making them sensiti...
ORGANISM(S): Homo Sapiens (ncbitaxon:9606) 
2025-03-06 | MSV000097246 | MassIVE
Sort   by:  
 Page size