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MetabolomicsMetabolomic profiling of Fraxinus excelsior genotypes tolerant or susceptible to ash dieback disease reveals changes in iridoid glycosides
European common ash, Fraxinus excelsior L., is currently threatened by Ash dieback (ADB) caused by the fungus, Hymenoscyphus fraxineus. To detect and identify metabolites that may be products of pathways important in contributing to resistance against H. fraxineus we performed untargeted metabolomic...
2016-11-09 | MTBLS372 | MetaboLights
TranscriptomicsTranscription profiling of melanized domamine neurons isolated from male and female patients with Parkinson disease to investigate gender differences
We used 500 melanized dopamine neurons isolated from post-mortem human substantia nigra pars compacta of each sample with laser capture microdissection. Total RNA was extracted with Arcturus PicoPure RNA extraction kit and amplified two times with Arcturus RiboAmp RNA amplification kit. the samples ...
ORGANISM(S): Homo sapiens 
2008-01-19 | E-MEXP-1416 | biostudies-arrayexpress
TranscriptomicsEpigenetic events in early breast cancer
Subpopulations of primary Human Mammary Epithelial Cells (HMEC) have the unique ability to escape a period of growth arrest and continue to proliferate. These cells, called post-selection or variant cells (vHMEC), share features with premalignant breast cancer lesions, including p16INK4A promoter h...
ORGANISM(S): Homo sapiens 
2010-05-26 | E-GEOD-8007 | biostudies-arrayexpress
ProteomicsCasz1 interactome via BioID on primary mouse retinal cells
Control versus Casz1 BioID on mouse primary retinal cells. BioID constructs were introduced via nucleofection. Cultured cells were harvested, nuclei extracted, and BioID was performed as per standard procedures.
ORGANISM(S): Mus Musculus (ncbitaxon:10090) 
2020-06-17 | MSV000085598 | MassIVE
TranscriptomicsTranscriptional profiling of six normal Angus tissues
Transcriptional profiling of six bovine tissues (small intestine, spleen, liver, adrenal gland, anterior pituitary, and thymus). Samples collected from each of 6 Angus steers at 14 months of age. Experiment was duplicated at two locations to measure reproducability of results. Six tissues, six biolo...
ORGANISM(S): Bos taurus 
2010-11-01 | E-GEOD-23837 | biostudies-arrayexpress
GenomicsEGAS00001000490-sc-20130516 - samples
DNA methylation has been shown to play a major role in determining cellular phenotype by regulating gene expression. Moreover, dysregulation of differentially methylated genes has been implicated in disease pathogenesis of various conditions including cancer development as well as autoimmune disease...
EGAD00001000394 | EGA
GenomicsSequencing component for the whole genome methylation analysis in PBMCs and cell subsets pilot study
DNA methylation has been shown to play a major role in determining cellular phenotype by regulating gene expression. Moreover, dysregulation of differentially methylated genes has been implicated in disease pathogenesis of various conditions including cancer development as well as autoimmune disease...
EGAS00001000490 | EGA
GenomicsDAC for study Sequencing component for the whole genome methylation analysis in PBMCs and cell subsets pilot study 1733-sc-2013-
Data Access Committee EGAC00001000096
EGAC00001000096 | EGA
TranscriptomicsEnrichment profiles of Ser-5 phosphorylated RNA polymerase II (PolII S5p) in mouse female ES cells
Many animal species employ a chromosome-based mechanism of sex determination, which has led to coordinate evolution of dosage compensation systems. Dosage compensation not only corrects the imbalance in the number of X-chromosomes between the sexes, but is also hypothesized to correct dosage imbalan...
ORGANISM(S): Mus musculus 
2011-07-18 | E-GEOD-30689 | biostudies-arrayexpress
Transcriptomics30% O2 vs PS 10W/m2
Comparison of wild-type (2.4.1) R. sphaeroides gene expression in 30% O2 aerobic respiration vs. photosynthesis 10W/m2 light, to identify candidate photosynthesis genes. RNA preparation: pellet cells from exponential phase cultures using 5% phenol in ethanol stop solution; lysozyme + SDS to lyse; p...
ORGANISM(S): Rhodobacter sphaeroides 
2010-06-10 | E-GEOD-2145 | biostudies-arrayexpress
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