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ProteomicsComprehensive identification of full-length mRNA isoforms reveals massive diversity of neural cell-surface molecules and illuminates their function in development and disease
Genes encoding cell-surface proteins are crucial for nervous system development and are implicated in neurological disorders. These genes produce alternative mRNA isoforms which remain poorly characterized, impeding our understanding of how disease-associated mutations cause pathology. Here we intro...
ORGANISM(S): Mus musculus (Mouse) 
2020-08-11 | PXD017290 | Pride
Cell-surface molecules Neural development Pacbio sequencing Isoforms 
TranscriptomicsBlood mRNA expression signatures derived from unsupervised analyses identify prostate cancers with poor outcome
Background: Inter-patient prostate cancer (PrCa) heterogeneity results in highly variable patient outcomes. Multi-purpose biomarkers to dissect this heterogeneity are urgently required to improve treatment and accelerate drug development in PrCa. Circulating biomarkers are most practical for evaluat...
ORGANISM(S): Homo sapiens 
2012-10-15 | E-GEOD-37199 | biostudies-arrayexpress
UnknownMethotrexate, Doxorubicin, and Cisplatin (MAP) Plus Maintenance Pegylated Interferon Alfa-2b Versus MAP Alone in Patients With Resectable High-Grade Osteosarcoma and Good Histologic Response to Preoperative MAP: First Results of the EURAMOS-1 Good Response Randomized Controlled Trial.
Not available
S-EPMC4486345 | biostudies-literature
GenomicsSMG
Severe malaria cases from Gambia
EGAD00000000018 | EGA
GenomicsCBC
Cord blood control samples from Gambia
EGAD00000000017 | EGA
GenomicsMalariaGEN case-control study in the Gambia
MalariaGEN case-control study in the Gambia.
EGAS00000000026 | EGA
GenomicsMalariaGEN data access committee
Access to individual-level genotype data is available by application to the MalariaGEN Independent Data Access Committee. Access to data will be granted to qualified investigators for appropriate use. For further information information on data release policy and data access application form, please...
EGAC00000000002 | EGA
TranscriptomicsThe consequences of rapid mating system evolution in crucifer genomes
We compare RNA expression and polymorphism patterns between C. rubella and its outcrossing progenitor C. grandiflora. There is a clear shift in the expression of genes associated with flowering phenotypes; a similar shift is seen in the related genus Arabidopsis, where self-fertilization evolved abo...
ORGANISM(S): Capsella grandiflora 
2013-03-28 | E-GEOD-45518 | biostudies-arrayexpress
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